Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.42 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 6/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.36 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.35 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.35 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9318105 | 0.88 | PLA2G2C (0.46) | PLA2G2CMCHR1KDM4EALDH1A1HPGD | |
| SCHEMBL14590755 | 0.88 | PLA2G2C (0.46) | PLA2G2CMCHR1KDM4EALDH1A1HPGD | |
| SCHEMBL11042332 | 0.85 | PLA2G2C (0.50) | PLA2G2CLPAR1LPAR3LPAR2PLA2G2A | |
| SCHEMBL11096065 | 0.85 | PLA2G2C (0.50) | PLA2G2CLPAR1LPAR3LPAR2PLA2G2A | |
| SCHEMBL11095547 | 0.85 | PLA2G2C (0.50) | PLA2G2CLPAR1LPAR3LPAR2PLA2G2A | |
| SCHEMBL11302375 | 0.85 | PLA2G2C (0.54) | PLA2G2CLPAR1LPAR3MCHR1KDM4E | |
| SCHEMBL10915388 | 0.85 | PLA2G2C (0.54) | PLA2G2CLPAR1LPAR3MCHR1KDM4E | |
| SCHEMBL11305106 | 0.84 | PLA2G2C (0.49) | PLA2G2CLPAR1LPAR3LPAR2PLA2G2A | |
| SCHEMBL19068464 | 0.82 | PLA2G2C (0.43) | PLA2G2CLPAR1LPAR3LPAR2PLA2G2A | |
| SCHEMBL10935379 | 0.81 | PLA2G2C (0.50) | PLA2G2CMCHR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4262021-A | INDUCERS OF PRODUCTION OF INTERFERON | PFIZER INC. (US) | 1981-04-14 | — | — | US | disclosed |
| US-4215146-A | Antiviral amine derivatives of glycerol and propanediols | PFIZER INC. (US) | 1980-07-29 | — | — | US | disclosed |
| US-4193999-A | Antiviral amine derivatives of propanediols | PFIZER INC. (US) | 1980-03-18 | — | — | US | disclosed |