Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 9/20 | 0.49 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.47 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.43 |
| ▸ | CETP | P11597 | 2/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11299859 | 1.00 | TLR2 (0.49) | TLR2PLA2G10PLA2G2ATDP1L3MBTL1 | |
| SCHEMBL16475725 | 1.00 | TLR2 (0.49) | TLR2PLA2G10PLA2G2ATDP1L3MBTL1 | |
| SCHEMBL11302097 | 0.94 | TLR2 (0.49) | TLR2PLA2G10PLA2G2ATDP1L3MBTL1 | |
| SCHEMBL11302100 | 0.94 | TLR2 (0.49) | TLR2PLA2G10PLA2G2ATDP1L3MBTL1 | |
| SCHEMBL16475732 | 0.94 | TLR2 (0.49) | TLR2PLA2G10PLA2G2ATDP1L3MBTL1 | |
| SCHEMBL25078765 | 0.90 | PLA2G10 (0.55) | TLR2PLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL13997509 | 0.90 | PLA2G10 (0.55) | TLR2PLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL2411920 | 0.90 | PLA2G10 (0.55) | TLR2PLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL4368865 | 0.90 | PLA2G10 (0.55) | TLR2PLA2G10PLA2G2APLA2G1BPLA2G5 | |
| SCHEMBL25078776 | 0.90 | PLA2G10 (0.55) | TLR2PLA2G10PLA2G2APLA2G1BPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3202760-B1 | PEGYLATED LIPIDS AND THEIR USE FOR DRUG DELIVERY | ALNYLAM PHARMACEUTICALS INC (US) | 2019-08-21 | — | — | EP | disclosed |
| US-9999673-B2 | PEGylated lipids and their use for drug delivery | ALNYLAM PHARMACEUTICALS, INC. (US) | 2018-06-19 | — | — | US | disclosed |
| EP-3202760-A1 | PEGYLATED LIPIDS AND THEIR USE FOR DRUG DELIVERY | Alnylam Pharmaceuticals, Inc. (US) | 2017-08-09 | — | — | EP | disclosed |
| EP-2663548-B1 | PEGYLATED LIPIDS AND THEIR USE FOR DRUG DELIVERY | ALNYLAM PHARMACEUTICALS INC (US) | 2017-04-05 | — | — | EP | disclosed |
| EP-2663548-A1 | PEGYLATED LIPIDS AND THEIR USE FOR DRUG DELIVERY | Alnylam Pharmaceuticals, Inc. (US) | 2013-11-20 | — | — | EP | disclosed |
| WO-2012099755-A1 | PEGYLATED LIPIDS AND THEIR USE FOR DRUG DELIVERY | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-07-26 | — | — | WO | disclosed |