Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | TTR | P02766 | 1/20 | 0.61 |
| ▸ | PPOX | P50336 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PYGL | P06737 | 2/20 | 0.44 |
| ▸ | CCR6 | P51684 | 2/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11304000 | 0.88 | MEN1 (0.72) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10996421 | 0.87 | TDP1 (0.73) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11306634 | 0.86 | MEN1 (0.68) | MEN1KMT2ATDP1TTRPPOX | |
| Acifluorfen-Methyl SCHEMBL31614705 | 0.83 | MEN1 (0.78) | MEN1KMT2ATDP1TTRPPOX | |
| Acifluorfen-Methyl SCHEMBL39092 | 0.83 | MEN1 (0.78) | MEN1KMT2ATDP1TTRPPOX | |
| Acifluorfen-Methyl SCHEMBL30749491 | 0.83 | MEN1 (0.78) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11297023 | 0.83 | TDP1 (0.67) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11297149 | 0.82 | TDP1 (0.68) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10996186 | 0.82 | TDP1 (0.68) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11298723 | 0.82 | TDP1 (0.79) | MEN1KMT2ATDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4263041-A | Optionally substituted phenyl, and alkyl N-[5-(2-chloro-4-trifluoromethyl-6-optionally substituted phenoxy)-2-nitro, halo, or cyanobenzoyl]carbamates | PPG INDUSTRIES, INC. (US) | 1981-04-21 | — | — | US | disclosed |