Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 6/20 | 0.43 |
| ▸ | MMP9 | P14780 | 6/20 | 0.43 |
| ▸ | MMP8 | P22894 | 6/20 | 0.43 |
| ▸ | MMP12 | P39900 | 6/20 | 0.43 |
| ▸ | MMP13 | P45452 | 6/20 | 0.43 |
| ▸ | MMP14 | P50281 | 5/20 | 0.43 |
| ▸ | MMP16 | P51512 | 5/20 | 0.43 |
| ▸ | MMP3 | P08254 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HAO1 | Q9UJM8 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292683 | 0.99 | HTT (0.43) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL11302157 | 0.99 | HTT (0.43) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL11295190 | 0.97 | HAO1 (0.43) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL11300195 | 0.96 | HAO1 (0.42) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL11295559 | 0.96 | HAO1 (0.42) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL11293603 | 0.96 | HAO1 (0.42) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL11299664 | 0.96 | HAO1 (0.44) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL11294207 | 0.96 | HAO1 (0.44) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL11295326 | 0.95 | HAO1 (0.43) | MMP2MMP9MMP8MMP12MMP13 | |
| SCHEMBL11291857 | 0.94 | HAO1 (0.44) | MMP2MMP9MMP8MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356325-A | Process for preparation of acetylene terminated sulfones, oligomers and precursors therefor | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1982-10-26 | — | — | US | disclosed |