Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 15/20 | 0.59 |
| ▸ | CTSB | P07858 | 3/20 | 0.59 |
| ▸ | CAPN9 | O14815 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CTSG | P08311 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CTSH | P09668 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSC | P53634 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209991 | 0.83 | CAPN1 (0.55) | CAPN1CTSBCTSLLMNACTSG | |
| SCHEMBL11302620 | 0.80 | CAPN1 (0.57) | CAPN1CTSBCAPN9MAPK1CTSL | |
| SCHEMBL11208847 | 0.80 | CAPN1 (0.69) | CAPN1CTSBCAPN9MAPK1CTSL | |
| SCHEMBL25313974 | 0.79 | CAPN1 (0.64) | CAPN1CTSBCAPN9MAPK1CTSL | |
| SCHEMBL22517716 | 0.79 | CAPN1 (0.67) | CAPN1CTSBCAPN9MAPK1CTSL | |
| SCHEMBL25310945 | 0.76 | CAPN1 (0.60) | CAPN1CTSBCAPN9MAPK1CTSL | |
| SCHEMBL11211366 | 0.74 | CAPN1 (0.61) | CAPN1CTSBCAPN9MAPK1CTSL | |
| E-64C SCHEMBL10750447 | 0.74 | CAPN1 (1.00) | CAPN1CTSBCAPN9MAPK1CTSL | |
| E-64C SCHEMBL10933522 | 0.74 | CAPN1 (1.00) | CAPN1CTSBCAPN9MAPK1CTSL | |
| E-64C SCHEMBL14067670 | 0.74 | CAPN1 (1.00) | CAPN1CTSBCAPN9MAPK1CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333879-A | CALCIUM-ACTIVATED NEUTRAL THIOLPROTEASE INHIBITOR USED IN THE TREATMENT OF MUSCULAR DYSTROPHY | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1982-06-08 | — | — | US | disclosed |