SCHEMBL11301701

SCHEMBL11301701

C=CCNC(=O)COc1ccccc1

nearest known ligand 0.88

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.88
GAA P10253 3/20 0.88
HTT P42858 2/20 0.88
RAB9A P51151 2/20 0.88
GLA P06280 1/20 0.88
KMT2A Q03164 3/20 0.61
HPGD P15428 1/20 0.61
KDM4E B2RXH2 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
MEN1 O00255 2/20 0.54
ALPL P05186 1/20 0.54
ALPI P09923 1/20 0.54
ALPG P10696 1/20 0.54
NPC1 O15118 2/20 0.54
USP2 O75604 1/20 0.54
POLB P06746 1/20 0.54
PKM P14618 1/20 0.54
ALDH1A1 P00352 1/20 0.53
LMNA P02545 1/20 0.53
ALOX15 P16050 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15652484 0.84 SMN1; SMN2 (0.69) SMN1; SMN2GAAHTTRAB9AGLA
SCHEMBL20024733 0.84 SMN1; SMN2 (0.69) SMN1; SMN2GAAHTTRAB9AGLA
SCHEMBL2562743 0.83 SMN1; SMN2 (0.68) SMN1; SMN2GAAHTTRAB9AGLA
SCHEMBL2556267 0.81 SMN1; SMN2 (0.61) SMN1; SMN2GAAHTTRAB9AGLA
SCHEMBL3368808 0.81 KMT2A (0.67) SMN1; SMN2GAAHTTRAB9AGLA
SCHEMBL10346480 0.80 CYP3A4 (0.72) SMN1; SMN2GAAHTTRAB9AGLA
SCHEMBL29229979 0.79 HTT (0.59) SMN1; SMN2GAAHTTRAB9AGLA
SCHEMBL11775788 0.79 KMT2A (0.69) SMN1; SMN2GAAHTTRAB9AGLA
SCHEMBL10948513 0.78 KMT2A (0.63) SMN1; SMN2GAAHTTRAB9AGLA
SCHEMBL10949439 0.78 USP2 (0.63) SMN1; SMN2GAAHTTRAB9AGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0002812-B1 PHENOXY-ALKYL OXAZOLINES, THEIR PREPARATION, COMPOSITIONS CONTAINING THEM AND THEIR APPLICATION AS HERBICIDES CIBA-GEIGY AG (CH) 1982-02-03 EP claimed
EP-0003297-B1 PHENOXY-ALKYL-OXAZOLINES, THEIR PREPARATION, HERBICIDE COMPOSITIONS CONTAINING THEM, AND THEIR APPLICATION CIBA-GEIGY AG (CH) 1981-05-13 EP claimed
CN-118834113-B Z-type enamide derivative and preparation method thereof 广东医科大学 2025-03-21 CN disclosed
CN-118834113-A Z-type enamide derivative and preparation method thereof 广东医科大学 2024-10-25 CN disclosed
CN-112724316-B Salt-tolerant temperature-resistant multipurpose thickening agent for shale gas reservoir volume reconstruction and preparation method thereof 中国石油天然气集团有限公司 2022-09-16 CN disclosed
CN-111607029-B Supermolecule oil displacement agent and preparation method thereof 中国石油化工股份有限公司 2021-10-15 CN disclosed
CN-112724316-A Salt-tolerant temperature-resistant multipurpose thickening agent for shale gas reservoir volume reconstruction and preparation method thereof 中国石油天然气集团有限公司 2021-04-30 CN disclosed
CN-111607029-A Supermolecule oil displacement agent and preparation method thereof 中国石油化工股份有限公司 2020-09-01 CN disclosed
CN-103555311-A AM/NaAA/APO (acrylamide/sodium acrylate/N-allylphenoxyacetamide) ternary polymer flooding agent and synthesis method UNIV SOUTHWEST PETROLEUM 2014-02-05 CN disclosed
US-4227914-A Herbicidal phenoxyalkyloxazolines CIBA-GEIGY CORPORATION (US) 1980-10-14 US disclosed
US-4225336-A Phenoxyalkyloxazolines, as selective herbicides in cereals CIBA-GEIGY CORPORATION (US) 1980-09-30 US disclosed
US-4119552-A DISPERSANT, AMIDATION OF PHENOXYALKANOIC ACID, REACTION OF THE AMIDE WITH A BORON COMPOUND EDWIN COOPER AND COMPANY LIMITED (GB) 1978-10-10 US disclosed