Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 5/20 | 0.46 |
| ▸ | SOS1 | Q07889 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EHMT2 | Q96KQ7 | 4/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | CCR4 | P51679 | 1/20 | 0.37 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11310184 | 0.83 | PDE10A (0.49) | PDE10ASOS1LMNAKMT2AEHMT2 | |
| SCHEMBL11307305 | 0.81 | PDE10A (0.59) | PDE10ALMNAKMT2APDE4APDE4B | |
| SCHEMBL11177928 | 0.81 | PDE10A (0.47) | PDE10ALMNAKMT2AEHMT2PDE4A | |
| SCHEMBL11184509 | 0.79 | CCR4 (0.40) | PDE10AKMT2AEHMT2CCR4EHMT1 | |
| SCHEMBL3056496 | 0.79 | PDE10A (0.47) | PDE10ASOS1LMNAKMT2APDE4A | |
| SCHEMBL11172076 | 0.79 | ENPP1 (0.47) | PDE10ALMNAKMT2A | |
| SCHEMBL11309885 | 0.79 | PDE10A (0.48) | PDE10ASOS1LMNAKMT2APDE4A | |
| SCHEMBL3059676 | 0.78 | PDE10A (0.55) | PDE10ASOS1LMNAKMT2A | |
| Oxalic Acid SCHEMBL11306727 | 0.78 | PDE10A (0.49) | PDE10ASOS1LMNAKMT2AEHMT2 | |
| Oxalic Acid SCHEMBL11174266 | 0.77 | PDE10A (0.40) | PDE10ASOS1EHMT2CCR4EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0017411-B1 | PHTHALAZINE CARDIAC STIMULANTS, PROCESSES FOR PREPARING THEM, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Pfizer Limited (GB) | 1982-03-31 | — | — | EP | disclosed |