Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 3/20 | 0.58 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | CISD1 | Q9NZ45 | 5/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 2/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11306890 | 1.00 | PLK1 (0.58) | PLK1ABL1PPARAEGFRSYK | |
| SCHEMBL11307721 | 1.00 | PLK1 (0.58) | PLK1ABL1PPARAEGFRSYK | |
| SCHEMBL11320571 | 1.00 | PLK1 (0.58) | PLK1ABL1PPARAEGFRSYK | |
| SCHEMBL11318599 | 1.00 | PLK1 (0.58) | PLK1ABL1PPARAEGFRSYK | |
| SCHEMBL11307858 | 1.00 | PLK1 (0.58) | PLK1ABL1PPARAEGFRSYK | |
| SCHEMBL11313036 | 1.00 | PLK1 (0.58) | PLK1ABL1PPARAEGFRSYK | |
| SCHEMBL11309283 | 1.00 | PLK1 (0.58) | PLK1ABL1PPARAEGFRSYK | |
| SCHEMBL11320812 | 1.00 | PLK1 (0.58) | PLK1ABL1PPARAEGFRSYK | |
| SCHEMBL11316566 | 1.00 | PLK1 (0.58) | PLK1ABL1PPARAEGFRSYK | |
| SCHEMBL11313449 | 1.00 | PLK1 (0.58) | PLK1ABL1PPARAEGFRSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4245119-A | ANTILIPEMIC AGENTS AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-01-13 | — | — | US | claimed |
| US-4245119-A | ANTILIPEMIC AGENTS AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-01-13 | — | — | US | disclosed |