Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.63 |
| ▸ | BRD2 | P25440 | 1/20 | 0.63 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.63 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5440674 | 0.90 | F2RL3 (0.63) | BRD4BRD2BRD3BRDTMAPT | |
| SCHEMBL17420647 | 0.86 | BRD4 (0.60) | BRD4BRD2BRD3BRDTMAPT | |
| SCHEMBL11316074 | 0.86 | BRD4 (0.70) | BRD4BRD2BRD3BRDTMAPT | |
| SCHEMBL23505872 | 0.82 | CA12 (0.51) | MAPTF2RL3ALDH1A1GAARAB9A | |
| SCHEMBL18295094 | 0.82 | F2RL3 (0.56) | MAPTF2RL3ALDH1A1SMN1; SMN2RECQL | |
| SCHEMBL12734333 | 0.81 | BRD4 (0.71) | BRD4BRD2BRD3BRDTMAPT | |
| SCHEMBL4245821 | 0.81 | KMT2A (0.49) | BRD4BRD2BRD3BRDTMAPT | |
| SCHEMBL30640876 | 0.81 | KMT2A (0.55) | BRD4BRD2BRD3BRDTMAPT | |
| SCHEMBL1617368 | 0.81 | BRD4 (0.70) | BRD4BRD2BRD3BRDTMAPT | |
| SCHEMBL6199097 | 0.79 | BRD4 (0.68) | BRD4BRD2BRD3BRDTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258052-A | APPLYING TOPICALLY | YU RUEY J | 1981-03-24 | — | — | US | claimed |
| US-10568913-B2 | Method for generating mature β-like cells | HEALTHREGEN PTY LTD (AU) | 2020-02-25 | — | — | US | disclosed |
| US-20160045554-A1 | METHOD FOR GENERATING MATURE BETA-LIKE CELLS | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2016-02-18 | — | — | US | disclosed |
| WO-2014153620-A1 | METHOD FOR GENERATING MATURE β-LIKE CELLS | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2014-10-02 | — | — | WO | disclosed |
| US-4258052-A | APPLYING TOPICALLY | YU RUEY J | 1981-03-24 | — | — | US | disclosed |