Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 3/20 | 0.53 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | PPARD | Q03181 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.43 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11308020 | 0.85 | SCN2A (0.48) | CA9SCN2ACA12CA1CA2 | |
| SCHEMBL11316620 | 0.80 | NPC1 (0.58) | KMT2AMEN1KDM4EGAARAB9A | |
| SCHEMBL9108451 | 0.78 | KMT2A (0.47) | KMT2AMEN1KDM4EGAA | |
| SCHEMBL13871737 | 0.76 | KMT2A (0.58) | CA9SCN2ACA12CA1CA2 | |
| SCHEMBL11565884 | 0.73 | KMT2A (0.55) | CA9SCN2ACA12CA1CA2 | |
| SCHEMBL10983149 | 0.73 | CA9 (0.48) | CA9SCN2ACA12CA1CA2 | |
| SCHEMBL4580181 | 0.73 | NR1H3 (0.62) | CA9SCN2ACA12CA1CA2 | |
| SCHEMBL6780924 | 0.72 | SCN2A (0.54) | CA9SCN2ACA12CA1CA2 | |
| SCHEMBL4649471 | 0.72 | KMT2A (0.78) | CA9SCN2ACA12CA1CA2 | |
| SCHEMBL22627090 | 0.72 | KMT2A (0.56) | CA9SCN2ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4308208-A | α-Methylthio-α-(p-phthalimidophenyl)-propionic acid | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1981-12-29 | — | — | US | claimed |
| US-4308208-A | α-Methylthio-α-(p-phthalimidophenyl)-propionic acid | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1981-12-29 | — | — | US | disclosed |
| US-4308208-A | α-Methylthio-α-(p-phthalimidophenyl)-propionic acid | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1981-12-29 | — | — | US | disclosed |
| US-4308208-A | α-Methylthio-α-(p-phthalimidophenyl)-propionic acid | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1981-12-29 | — | — | US | disclosed |
| US-4278802-A | METHYLTHIO-/P-/2-THIENYLCARBONYL/PHENYL/PROPIONIC ACID OR ESTER, PHARMACEUTICAL INTERMEDIATES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1981-07-14 | — | — | US | disclosed |
| US-4242519-A | DRUG INTERMEDIATES | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1980-12-30 | — | — | US | disclosed |