Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11315540 | 0.97 | PTGIR (0.45) | PTGIRMAPTTHRBTP53TSHR | |
| SCHEMBL11313069 | 0.96 | PTGIR (0.48) | PTGIRMAPTTHRBTP53TSHR | |
| SCHEMBL11225954 | 0.94 | PTGIR (0.46) | PTGIRMAPTTHRBTP53TSHR | |
| SCHEMBL11314317 | 0.90 | PTGIR (0.52) | PTGIRTP53TSHRPDE4BPDK1 | |
| SCHEMBL11363149 | 0.89 | MAPT (0.42) | PTGIRMAPTTHRBTP53TSHR | |
| SCHEMBL11321942 | 0.88 | PTGIR (0.39) | PTGIRNPC1RAB9AALDH1A1 | |
| SCHEMBL11311657 | 0.87 | PTGIR (0.51) | PTGIRTP53TSHRPDE4BPDK1 | |
| SCHEMBL11310893 | 0.87 | MAPT (0.42) | PTGIRMAPTTHRBTP53TSHR | |
| Clanobutin SCHEMBL667903 | 0.85 | PTGIR (0.56) | PTGIRTP53TSHRPDE4BLMNA | |
| Clanobutin SCHEMBL5055263 | 0.85 | PTGIR (0.56) | PTGIRTP53TSHRPDE4BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250183-A | GASTOINTESTINAL DISORDERS; DISEASES OF THE PANCREAS, GALL BLADDER, AND LIVER | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-02-10 | — | — | US | claimed |
| US-4250183-A | GASTOINTESTINAL DISORDERS; DISEASES OF THE PANCREAS, GALL BLADDER, AND LIVER | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-02-10 | — | — | US | disclosed |