Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 3/20 | 0.48 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PNLIP | P16233 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11316361 | 1.00 | PLK1 (0.48) | PLK1EGFRTSHRLMNAALDH1A1 | |
| SCHEMBL11306884 | 1.00 | PLK1 (0.48) | PLK1EGFRTSHRLMNAALDH1A1 | |
| SCHEMBL11313529 | 1.00 | PLK1 (0.48) | PLK1EGFRTSHRLMNAALDH1A1 | |
| SCHEMBL11319758 | 1.00 | PLK1 (0.48) | PLK1EGFRTSHRLMNAALDH1A1 | |
| SCHEMBL11307809 | 1.00 | PLK1 (0.48) | PLK1EGFRTSHRLMNAALDH1A1 | |
| SCHEMBL11313424 | 1.00 | PLK1 (0.48) | PLK1EGFRTSHRLMNAALDH1A1 | |
| SCHEMBL11318044 | 1.00 | PLK1 (0.48) | PLK1EGFRTSHRLMNAALDH1A1 | |
| SCHEMBL11307880 | 1.00 | PLK1 (0.48) | PLK1EGFRTSHRLMNAALDH1A1 | |
| SCHEMBL11315370 | 1.00 | PLK1 (0.48) | PLK1EGFRTSHRLMNAALDH1A1 | |
| SCHEMBL11310309 | 1.00 | PLK1 (0.48) | PLK1EGFRTSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4245120-A | ANTILIPIMIC AGENTS AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-01-13 | — | — | US | disclosed |
| US-4245119-A | ANTILIPEMIC AGENTS AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-01-13 | — | — | US | disclosed |