Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 6/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.40 |
| ▸ | BPTF | Q12830 | 2/20 | 0.40 |
| ▸ | BRD1 | O95696 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.40 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11313995 | 1.00 | CHRM4 (0.44) | CHRM4CHRM3BRD4SLC6A2SLC6A4 | |
| SCHEMBL11313990 | 1.00 | CHRM4 (0.44) | CHRM4CHRM3BRD4SLC6A2SLC6A4 | |
| SCHEMBL11321792 | 0.80 | CHRM4 (0.52) | CHRM4CHRM3BRD4CYP2D6 | |
| SCHEMBL11321796 | 0.80 | CHRM4 (0.52) | CHRM4CHRM3BRD4CYP2D6 | |
| SCHEMBL11321790 | 0.80 | CHRM4 (0.52) | CHRM4CHRM3BRD4CYP2D6 | |
| SCHEMBL16838803 | 0.79 | SLC6A4 (0.41) | BRD4SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL16838802 | 0.79 | SLC6A4 (0.41) | BRD4SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL21321770 | 0.79 | SLC6A4 (0.41) | BRD4SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL9910977 | 0.79 | BRD4 (0.53) | BRD4SLC6A2SLC6A4SLC6A3SRD5A1 | |
| SCHEMBL28593173 | 0.79 | CHRM4 (0.51) | CHRM4CHRM3BRD4KAT2BBRD9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4248876-A | Piperidine derivatives | JOHN WYETH & BROTHER LTD. (GB) | 1981-02-03 | — | — | US | disclosed |