Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 4/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | BAD | Q92934 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1226198 | 0.89 | PTGS1 (0.54) | PTGS1KIF11MAOBHSD17B1SMN1; SMN2 | |
| SCHEMBL10436026 | 0.86 | MAOB (0.55) | PTGS1KIF11MAOBHSD17B1SMN1; SMN2 | |
| SCHEMBL30747689 | 0.86 | MAOB (0.55) | PTGS1KIF11MAOBHSD17B1SMN1; SMN2 | |
| SCHEMBL2555397 | 0.84 | MAPT (0.48) | PTGS1KIF11MAOBHSD17B1SMN1; SMN2 | |
| SCHEMBL22926305 | 0.84 | FASN (0.51) | PTGS1KIF11MAOBHSD17B1SMN1; SMN2 | |
| SCHEMBL16156050 | 0.84 | PTGS1 (0.53) | PTGS1KIF11MAOBHSD17B1SMN1; SMN2 | |
| SCHEMBL1222849 | 0.84 | BCL2L1 (0.62) | SMN1; SMN2KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL4991368 | 0.82 | PTGS1 (0.54) | PTGS1MAPTALDH1A1MAP4K4 | |
| SCHEMBL26116358 | 0.81 | PTGS1 (0.57) | PTGS1SMN1; SMN2MAPTKDM4EMEN1 | |
| SCHEMBL2556102 | 0.81 | PTGS1 (0.50) | PTGS1KIF11MAOBHSD17B1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2295402-B1 | Antibacterial agents | UNIV WASHINGTON (US) | 2015-08-12 | — | — | EP | disclosed |
| US-4301313-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS | ELI-LILLY AND COMPANY (US) | 1981-11-17 | — | — | US | disclosed |
| US-4226887-A | P-BIPHENYLYLACETYLENE | ELI LILLY AND COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
| US-3991212-A | PHENYLACETYLENE COMPOUNDS | ELI LILLY AND COMPANY (US) | 1976-11-09 | — | — | US | disclosed |
| US-3968251-A | Arylacetylene compounds as antithrombotic agents | ELI LILLY AND COMPANY (US) | 1976-07-06 | — | — | US | disclosed |