Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 7/20 | 0.71 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.71 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.71 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.71 |
| ▸ | PDE3B | Q13370 | 17/20 | 0.60 |
| ▸ | PDE3A | Q14432 | 17/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427721 | 0.83 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL11318875 | 0.78 | PDE4A (0.72) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL10597216 | 0.78 | PDE3B (0.68) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL11317512 | 0.78 | PDE3B (0.68) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL7483850 | 0.78 | PDE3B (0.70) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL11082523 | 0.76 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL11314887 | 0.76 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL11328059 | 0.75 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL11093447 | 0.74 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DPDE3B | |
| SCHEMBL9730914 | 0.73 | PDE3B (0.84) | PDE4APDE4BPDE4CPDE4DPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258185-A | HYPOTENSIVE, ANTITHROMBOTIC AGENTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1981-03-24 | — | — | US | disclosed |