SCHEMBL11316645

SCHEMBL11316645

CC(=O)CC(C)(OO)OOC(C)(CC(C)=O)OO.CC(C)CC(C)(OO)OOC(C)(CC(C)C)OO

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MMP8 P22894 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL72719 0.86 TSHR (0.50) TSHRALDH1A1TDP1
SCHEMBL35002 0.84 TSHR (0.52) TSHRALDH1A1MMP8
Tert-Butyl Hydroperoxide SCHEMBL11199804 0.82 TSHR (0.46) TSHRALDH1A1TDP1
SCHEMBL6847874 0.80 TSHR (0.38) TSHRMMP8
SCHEMBL2460285 0.79 TSHR (0.43) TSHR
SCHEMBL11313847 0.79 TSHR (0.67) TSHRALDH1A1TDP1
SCHEMBL14861984 0.77 TSHR (0.41) TSHR
SCHEMBL6841235 0.75 TSHR (0.36) TSHRMMP8
SCHEMBL7640810 0.75 TSHR (0.43) TSHRALDH1A1MMP8
SCHEMBL6844542 0.73 TSHR (0.34) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4299718-A IN SITU PEROXIDATION OF KETONES IN A KETONE PEROXIDE SOLVENT FORMULATION MONTEDISON S.P.A. (IT) 1981-11-10 US claimed