SCHEMBL11316883

SCHEMBL11316883

O=C(O)CSSC(Cl)(Cl)Cl

nearest known ligand 0.55

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.55
CYP2D6 P10635 2/20 0.55
HIF1A Q16665 1/20 0.41
TSHR P16473 3/20 0.33
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
HSD17B10 Q99714 1/20 0.32
PHGDH O43175 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
FFAR1 O14842 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6584433 0.74 CYP2D6 (0.55) CYP2C19CYP2D6HIF1ATSHRHSD17B10
SCHEMBL298385 0.73 CYP2D6 (1.00) CYP2C19CYP2D6HIF1ATSHRCYP1A2
SCHEMBL9588186 0.70 CYP2D6 (0.50) CYP2C19CYP2D6HIF1ATSHRHSD17B10
Ammonia Solution, Strong SCHEMBL27893881 0.70 CYP2D6 (0.92) CYP2C19CYP2D6HIF1ATSHRCYP1A2
Hydrochloric Acid SCHEMBL11150442 0.70 CYP2D6 (0.92) CYP2C19CYP2D6HIF1ATSHRCYP1A2
SCHEMBL3815956 0.67 CYP2D6 (0.73) CYP2C19CYP2D6HIF1ATSHRCYP1A2
Ethylene SCHEMBL28577445 0.67 CYP2D6 (0.86) CYP2C19CYP2D6HIF1ATSHRCYP1A2
SCHEMBL11256098 0.67 CYP2D6 (0.46) CYP2C19CYP2D6HIF1ATSHRCYP1A2
SCHEMBL11314320 0.67
SCHEMBL2912849 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4266033-A Cellulose fermentation process CHEVRON RESEARCH COMPANY (US) 1981-05-05 US claimed
US-4219673-A 2-(Trichloromethyldithio)acetic acid and related compounds CHEVRON RESEARCH COMPANY (US) 1980-08-26 US claimed
US-4110475-A A 2-(CHLOROMETHYLDITHIO)ACETIC ACID CHEVRON RESEARCH COMPANY (US) 1978-08-29 US claimed
US-4266033-A Cellulose fermentation process CHEVRON RESEARCH COMPANY (US) 1981-05-05 US disclosed
US-4219673-A 2-(Trichloromethyldithio)acetic acid and related compounds CHEVRON RESEARCH COMPANY (US) 1980-08-26 US disclosed
US-4219673-A 2-(Trichloromethyldithio)acetic acid and related compounds CHEVRON RESEARCH COMPANY (US) 1980-08-26 US disclosed
US-4110475-A A 2-(CHLOROMETHYLDITHIO)ACETIC ACID CHEVRON RESEARCH COMPANY (US) 1978-08-29 US disclosed