Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792896 | 0.96 | GAA (0.53) | MAPTGAAPOLBTOP2AL3MBTL1 | |
| SCHEMBL6829598 | 0.94 | GAA (0.51) | MAPTGAAPOLBL3MBTL1KMT2A | |
| SCHEMBL3140172 | 0.91 | MAPT (0.58) | MAPTGAAPOLBTOP2AL3MBTL1 | |
| SCHEMBL11317810 | 0.88 | MAPT (0.61) | MAPTGAAL3MBTL1KMT2APTPN1 | |
| SCHEMBL14570539 | 0.86 | TOP2A (0.53) | MAPTGAAPOLBTOP2APTPN1 | |
| SCHEMBL23673305 | 0.84 | TOP2A (0.51) | MAPTPOLBTOP2AKYAT1ALDH1A1 | |
| SCHEMBL4823915 | 0.84 | TOP2A (0.51) | MAPTPOLBTOP2AALDH1A1HTT | |
| SCHEMBL23673315 | 0.84 | MAPT (0.51) | MAPTGAAPOLBTOP2AKMT2A | |
| SCHEMBL15383209 | 0.84 | MAPT (0.57) | MAPTGAAPOLBTOP2AL3MBTL1 | |
| SCHEMBL5009825 | 0.83 | TOP2A (0.64) | MAPTGAATOP2AALDH1A1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4250183-A | GASTOINTESTINAL DISORDERS; DISEASES OF THE PANCREAS, GALL BLADDER, AND LIVER | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-02-10 | — | — | US | disclosed |