Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 8/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11308122 | 0.91 | GAA (0.66) | GAAHTTHPGDKDM4EALDH1A1 | |
| SCHEMBL11323163 | 0.91 | GAA (0.66) | GAAHTTHPGDKDM4EALDH1A1 | |
| SCHEMBL11349180 | 0.91 | GAA (0.61) | GAAHTTHPGDKDM4EALDH1A1 | |
| SCHEMBL7419408 | 0.90 | GAA (0.74) | GAAHTTHPGDKDM4EALDH1A1 | |
| SCHEMBL11303540 | 0.90 | GAA (0.69) | GAAHTTHPGDKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11323166 | 0.90 | GAA (0.64) | GAAHTTHPGDKDM4EALDH1A1 | |
| SCHEMBL8900419 | 0.89 | GAA (0.72) | GAAHTTHPGDKDM4EALDH1A1 | |
| SCHEMBL27808161 | 0.89 | GAA (0.57) | GAAHTTHPGDKDM4EALDH1A1 | |
| SCHEMBL2476221 | 0.89 | GAA (0.62) | GAAHTTHPGDKDM4EALDH1A1 | |
| SCHEMBL70011 | 0.88 | GAA (0.58) | GAAHTTHPGDKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4297503-A | CHEMICAL INTERMEDIATE FOR METOCLOPRAMIDE | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1981-10-27 | — | — | US | disclosed |
| US-4279836-A | Hydroxamic acid derivative and method of preparing metoclopramide using same | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1981-07-21 | — | — | US | disclosed |
| US-4250110-A | FROM 2-CHLORO-4-N-(B-DIETHYLAMINOETHYL)AMINOCARBONYL-5-METHOXY-BENZAMIDE | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1981-02-10 | — | — | US | disclosed |