SCHEMBL11318302

SCHEMBL11318302

CC(=NO)c1cc(C(C)=NO)cc(C(C)=NO)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
GFER P55789 2/20 0.45
POLB P06746 1/20 0.45
CASP3 P42574 1/20 0.45
SENP8 Q96LD8 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
MAPT P10636 5/20 0.43
CYP2C19 P33261 2/20 0.43
RAB9A P51151 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
KDM4E B2RXH2 4/20 0.42
HPGD P15428 3/20 0.42
HTT P42858 2/20 0.42
FURIN P09958 1/20 0.41
LMNA P02545 4/20 0.41
KMT2A Q03164 2/20 0.41
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15761095 0.83 NPSR1 (0.48) NPSR1SMN1; SMN2GFERPOLBCASP3
SCHEMBL17134274 0.83 NPSR1 (0.48) NPSR1SMN1; SMN2GFERPOLBCASP3
SCHEMBL15761187 0.81 NPSR1 (0.47) NPSR1SMN1; SMN2GFERPOLBCASP3
SCHEMBL7622154 0.81 KMT2A (0.47) NPSR1SMN1; SMN2GFERPOLBCASP3
SCHEMBL8661356 0.81 KMT2A (0.47) NPSR1SMN1; SMN2GFERPOLBCASP3
SCHEMBL14330299 0.81 SMN1; SMN2 (0.57) NPSR1SMN1; SMN2GFERPOLBCASP3
SCHEMBL13927326 0.81 SMN1; SMN2 (0.57) NPSR1SMN1; SMN2GFERPOLBCASP3
SCHEMBL17133975 0.81 NPSR1 (0.47) NPSR1SMN1; SMN2GFERPOLBCASP3
SCHEMBL12360950 0.80 CA9 (0.52) NPSR1SMN1; SMN2GFERPOLBCASP3
SCHEMBL14298196 0.80 CA9 (0.52) NPSR1SMN1; SMN2GFERPOLBCASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4157450-A Benzene-1,3,5-tris-acetoxime and the process for making phloroglucinol therewith AKZONA INCORPORATED (US) 1979-06-05 US claimed
US-4115451-A Benzene-1,3,5-tris-acetoxime and the process for making phloroglucinol therewith AKZONA INCORPORATED (US) 1978-09-19 US claimed
US-4071555-A Benzene-1,3,5-tris-acetoxime and the process for making phloroglucinol therewith AKZONA INCORPORATED (US) 1978-01-31 US claimed
US-4296260-A Process for the preparation of phloroglucinol AKZONA INCORPORATED (US) 1981-10-20 US disclosed
US-4157450-A Benzene-1,3,5-tris-acetoxime and the process for making phloroglucinol therewith AKZONA INCORPORATED (US) 1979-06-05 US disclosed
US-4157450-A Benzene-1,3,5-tris-acetoxime and the process for making phloroglucinol therewith AKZONA INCORPORATED (US) 1979-06-05 US disclosed
US-4157450-A Benzene-1,3,5-tris-acetoxime and the process for making phloroglucinol therewith AKZONA INCORPORATED (US) 1979-06-05 US disclosed
US-4115451-A Benzene-1,3,5-tris-acetoxime and the process for making phloroglucinol therewith AKZONA INCORPORATED (US) 1978-09-19 US disclosed
US-4115451-A Benzene-1,3,5-tris-acetoxime and the process for making phloroglucinol therewith AKZONA INCORPORATED (US) 1978-09-19 US disclosed
US-4115451-A Benzene-1,3,5-tris-acetoxime and the process for making phloroglucinol therewith AKZONA INCORPORATED (US) 1978-09-19 US disclosed
US-4071555-A Benzene-1,3,5-tris-acetoxime and the process for making phloroglucinol therewith AKZONA INCORPORATED (US) 1978-01-31 US disclosed
US-4071555-A Benzene-1,3,5-tris-acetoxime and the process for making phloroglucinol therewith AKZONA INCORPORATED (US) 1978-01-31 US disclosed
US-4071555-A Benzene-1,3,5-tris-acetoxime and the process for making phloroglucinol therewith AKZONA INCORPORATED (US) 1978-01-31 US disclosed