Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.70 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.70 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | CDC25B | P30305 | 1/20 | 0.54 |
| ▸ | PRNP | P04156 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | ATIC | P31939 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27985 | 0.97 | NR4A1 (0.73) | NR4A1NR4A2NR4A3ALDH1A1ALOX15 | |
| SCHEMBL29406795 | 0.97 | NR4A1 (0.73) | NR4A1NR4A2NR4A3ALDH1A1ALOX15 | |
| SCHEMBL28561641 | 0.94 | NR4A1 (0.70) | NR4A1NR4A2NR4A3ALDH1A1ALOX15 | |
| SCHEMBL29067052 | 0.94 | NR4A1 (0.70) | NR4A1NR4A2NR4A3ALDH1A1ALOX15 | |
| SCHEMBL28397149 | 0.94 | NR4A1 (0.70) | NR4A1NR4A2NR4A3ALDH1A1ALOX15 | |
| SCHEMBL29067055 | 0.94 | NR4A1 (0.70) | NR4A1NR4A2NR4A3ALDH1A1ALOX15 | |
| SCHEMBL30570940 | 0.94 | NR4A1 (0.70) | NR4A1NR4A2NR4A3ALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL2457250 | 0.94 | NR4A1 (0.70) | NR4A1NR4A2NR4A3ALDH1A1ALOX15 | |
| SCHEMBL28397214 | 0.94 | NR4A1 (0.70) | NR4A1NR4A2NR4A3ALDH1A1ALOX15 | |
| SCHEMBL28400347 | 0.94 | NR4A1 (0.70) | NR4A1NR4A2NR4A3ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512905-B1 | METHOD FOR PRODUCING A POLYBENZAZOL POLYMER (P) | BASF SE (DE) | 2022-08-24 | — | — | EP | disclosed |
| US-4278786-A | BIS/P-AMINOPHENOL ETHER OF A BISPHENOL | HITACHI, LTD. (JP) | 1981-07-14 | — | — | US | disclosed |