SCHEMBL1131891

SCHEMBL1131891

C=CCOC(=O)c1ccccc1O.[NaH]

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.77
ALDH1A1 P00352 4/20 0.66
HSD17B10 Q99714 3/20 0.66
TSHR P16473 2/20 0.66
TDP1 Q9NUW8 2/20 0.59
LMNA P02545 2/20 0.50
KMT2A Q03164 2/20 0.48
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
HTT P42858 1/20 0.48
HPGD P15428 3/20 0.47
ALOX15 P16050 1/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
RHOA P61586 1/20 0.46
KDM4E B2RXH2 2/20 0.44
ADRB2 P07550 1/20 0.43
ADRB1 P08588 1/20 0.43
ADRB3 P13945 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL64356 0.98 CYP3A4 (0.79) CYP3A4ALDH1A1HSD17B10TSHRTDP1
SCHEMBL27522934 0.98 CYP3A4 (0.79) CYP3A4ALDH1A1HSD17B10TSHRTDP1
SCHEMBL1889642 0.97 CYP3A4 (0.77) CYP3A4ALDH1A1HSD17B10TSHRTDP1
SCHEMBL2788246 0.97 CYP3A4 (0.77) CYP3A4ALDH1A1HSD17B10TSHRTDP1
SCHEMBL5756387 0.97 CYP3A4 (0.77) CYP3A4ALDH1A1HSD17B10TSHRTDP1
SCHEMBL669635 0.97 CYP3A4 (0.77) CYP3A4ALDH1A1HSD17B10TSHRTDP1
SCHEMBL18259144 0.97 CYP3A4 (0.77) CYP3A4ALDH1A1HSD17B10TSHRTDP1
SCHEMBL6261194 0.97 CYP3A4 (0.77) CYP3A4ALDH1A1HSD17B10TSHRTDP1
SCHEMBL1426600 0.97 CYP3A4 (0.77) CYP3A4ALDH1A1HSD17B10TSHRTDP1
SCHEMBL7068227 0.97 CYP3A4 (0.77) CYP3A4ALDH1A1HSD17B10TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115141674-B Extreme pressure antiwear lubricating oil and preparation method thereof 贝源新材料科技(广东)有限公司 2023-06-13 CN claimed
CN-115141674-A Extreme pressure antiwear lubricating oil and preparation method thereof 贝源新材料科技(广东)有限公司 2022-10-04 CN claimed
CN-101195785-B Preparation method of alkyl sodium salicylate metal detergent CHINA NAT PETROLEUM CORP 2010-05-19 CN claimed
CN-101195785-A Preparation method of alkyl sodium salicylate metal detergent CHINA NAT PETROLEUM CORP (CN) 2008-06-11 CN claimed
CN-116515543-B High-dispersion stable lubricating oil metal detergent and preparation method thereof 湖南鸿福实业有限公司 2024-04-02 CN disclosed
CN-116515543-A High-dispersion stable lubricating oil metal detergent and preparation method thereof 湖南鸿福实业有限公司 2023-08-01 CN disclosed
CN-116478748-A Preparation method of neutral salicylate detergent 中国石油天然气股份有限公司 2023-07-25 CN disclosed
CN-115141674-B Extreme pressure antiwear lubricating oil and preparation method thereof 贝源新材料科技(广东)有限公司 2023-06-13 CN disclosed
CN-115141674-A Extreme pressure antiwear lubricating oil and preparation method thereof 贝源新材料科技(广东)有限公司 2022-10-04 CN disclosed
CN-112574721-A Multi-effect environment-friendly glycol type automobile cooling liquid and preparation method thereof 江苏艾德露环保科技有限公司 2021-03-30 CN disclosed
CN-112538339-A Engine coolant 山东泰和水处理科技股份有限公司 2021-03-23 CN disclosed
EP-1819804-B1 Emulsifier blends for lubricating oils CHEMTURA CORP (US) 2011-02-16 EP disclosed
US-5064545-A REACTING OIL SOLUBLE ORGANIC ACIDS WITH METAL OXIDES OR HYDROXIDES, BORIC ACID, AND PROMOTERS THE LUBRIZOL CORPORATION (US) 1991-11-12 US disclosed
EP-0295278-B1 A PROCESS FOR OVERBASING VIA METAL BORATE FORMATION The Lubrizol Corporation (US) 1991-05-08 EP disclosed
US-4987273-A REVERSE OSMOSIS SHELL OIL COMPANY (US) 1991-01-22 US disclosed
EP-0370555-A2 A process for the separation of a phenol SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1990-05-30 EP disclosed
EP-0295278-A1 A PROCESS FOR OVERBASING VIA METAL BORATE FORMATION. LUBRIZOL CORP (US) 1988-12-21 EP disclosed
US-4765800-A SUCCINIC ACID DERIVATIVE WITH HYDROCARBON SUBSTITUENT AS ADDITIVE SHELL OIL COMPANY (US) 1988-08-23 US disclosed
WO-1988004685-A2 A PROCESS FOR OVERBASING VIA METAL BORATE FORMATION THE LUBRIZOL CORPORATION (US) 1988-06-30 WO disclosed
EP-0207560-A1 Gasoline composition SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1987-01-07 EP disclosed