Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 1.00 |
| ▸ | ESR1 | P03372 | 4/20 | 0.65 |
| ▸ | AR | P10275 | 4/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.65 |
| ▸ | SHBG | P04278 | 1/20 | 0.58 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11514201 | 1.00 | CYP19A1 (1.00) | CYP19A1ESR1ARESR2SHBG | |
| SCHEMBL9694107 | 1.00 | CYP19A1 (1.00) | CYP19A1ESR1ARESR2SHBG | |
| SCHEMBL15164608 | 0.83 | CYP19A1 (0.71) | CYP19A1ESR1ARESR2 | |
| SCHEMBL15164651 | 0.83 | CYP19A1 (0.71) | CYP19A1ESR1ARESR2 | |
| SCHEMBL12178028 | 0.83 | CYP19A1 (0.71) | CYP19A1SHBGSERPINA6 | |
| SCHEMBL2590991 | 0.83 | CYP19A1 (0.71) | CYP19A1ESR1ARESR2 | |
| SCHEMBL2593080 | 0.83 | CYP19A1 (0.71) | CYP19A1SHBGSERPINA6 | |
| SCHEMBL2590989 | 0.83 | CYP19A1 (0.71) | CYP19A1ESR1ARESR2 | |
| SCHEMBL11518145 | 0.82 | CYP19A1 (0.70) | CYP19A1ESR1ARESR2SHBG | |
| SCHEMBL8623817 | 0.82 | CYP19A1 (0.70) | CYP19A1ESR1ARESR2SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4272445-A | STEROIDS, BASIC CATALYSTS, ALKYLATION | BEECHAM GROUP LIMITED (GB) | 1981-06-09 | — | — | US | claimed |