Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 9/20 | 0.58 |
| ▸ | EGFR | P00533 | 9/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 9/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 9/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 9/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 9/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 9/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 9/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.54 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11200379 | 0.88 | HDAC3 (0.59) | HDAC3EGFRHDAC4HDAC1HDAC7 | |
| SCHEMBL11216552 | 0.88 | HDAC3 (0.59) | HDAC3EGFRHDAC4HDAC1HDAC7 | |
| SCHEMBL11212802 | 0.88 | HDAC3 (0.59) | HDAC3EGFRHDAC4HDAC1HDAC7 | |
| SCHEMBL11218084 | 0.88 | HDAC3 (0.59) | HDAC3EGFRHDAC4HDAC1HDAC7 | |
| SCHEMBL11203184 | 0.88 | HDAC3 (0.59) | HDAC3EGFRHDAC4HDAC1HDAC7 | |
| SCHEMBL11214314 | 0.87 | HDAC3 (0.57) | HDAC3EGFRHDAC4HDAC1HDAC7 | |
| SCHEMBL10954456 | 0.85 | KDM4C (0.60) | HDAC3EGFRHDAC4HDAC1HDAC7 | |
| SCHEMBL16131268 | 0.85 | KDM4C (0.60) | HDAC3EGFRHDAC4HDAC1HDAC7 | |
| SCHEMBL10601781 | 0.85 | KDM4C (0.60) | HDAC3EGFRHDAC4HDAC1HDAC7 | |
| SCHEMBL10954583 | 0.85 | KDM4C (0.60) | HDAC3EGFRHDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4306930-A | INCORPORATING A HYDRAZIDE OR DIHYDRAZIDE AND THEN VULCANIZING IN CONTACT WITH A METAL | CIBA-GEIGY CORPORATION (US) | 1981-12-22 | — | — | US | disclosed |
| US-4077948-A | N-SALICYLIDENE-N*-SALICYLHYDRAZIDES | CIBA-GEIGY CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |