⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1132266 | 1.00 | — | — | |
| SCHEMBL14981453 | 1.00 | — | — | |
| SCHEMBL346613 | 0.71 | — | — | |
| SCHEMBL11205436 | 0.71 | — | — | |
| SCHEMBL346612 | 0.71 | — | — | |
| SCHEMBL2019398 | 0.64 | — | — | |
| SCHEMBL4891537 | 0.64 | — | — | |
| SCHEMBL1639141 | 0.64 | — | — | |
| SCHEMBL5699320 | 0.64 | — | — | |
| SCHEMBL4891533 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240009169-A9 | PPARG Modulators for the Treatment of Osteoporosis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2024-01-11 | — | — | US | disclosed |
| US-20230072933-A1 | PPARG Modulators for the Treatment of Osteoporosis | SCRIPPS RESEARCH INST (US) | 2023-03-09 | — | — | US | disclosed |
| US-20200369665-A1 | IMIDAZO[1,2-A]PYRAZINE MODULATORS OF THE ADENOSINE A2A RECEPTOR | Ryvu Therapeutics S.A. (PL) | 2020-11-26 | — | — | US | disclosed |
| US-10744117-B2 | PPARG modulators for the treatment of osteoporosis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-08-18 | — | — | US | disclosed |
| EP-3645536-A1 | IMIDAZO[1,2-A]PYRAZINE MODULATORS OF THE ADENOSINE A2A RECEPTOR | Ryvu Therapeutics S.A. (PL) | 2020-05-06 | — | — | EP | disclosed |
| CN-110809577-A | Modulators of adenosine A2A receptor | 雷沃医疗有限公司 | 2020-02-18 | — | — | CN | disclosed |
| WO-2019002606-A1 | IMIDAZO[1,2-A]PYRAZINE MODULATORS OF THE ADENOSINE A2A RECEPTOR | SELVITA S.A. (PL) | 2019-01-03 | — | — | WO | disclosed |
| US-20180369196-A1 | PPARG Modulators for the Treatment of Osteoporosis | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2018-12-27 | — | — | US | disclosed |
| US-10016394-B2 | PPARG modulators for treatment of osteoporosis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2018-07-10 | — | — | US | disclosed |
| EP-2513028-B1 | METHOD FOR PREPARING ALIZARIN DERIVATIVE COMPOUND, NOVEL ALIZARIN DERIVATIVE COMPOUND, USE OF SAID ALIZARIN COMPOUND, PHOTOELECTRIC CONVERSION FILM, PHOTOELECTRIC CONVERSION ELEMENT, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR | FUJIFILM CORP (JP) | 2018-06-20 | — | — | EP | disclosed |
| EP-2287155-A1 | ACYLTHIOUREA COMPOUND OR SALT THEREOF, AND USE OF THE COMPOUND OR THE SALT | Taiho Pharmaceutical Co., Ltd. (JP) | 2011-02-23 | — | — | EP | disclosed |
| US-20110034439-A1 | ACYLTHIOUREA COMPOUND OR SALT THEREOF, AND USE THEREOF | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2011-02-10 | — | — | US | disclosed |
| WO-2008099904-A1 | SILANE COMPOUND, PRODUCTION METHOD THEREOF, AND RESIN COMPOSITION CONTAINING SILANE COMPOUND | NIPPON SHOKUBAI CO., LTD. (JP) | 2008-08-21 | — | — | WO | disclosed |
| EP-0837933-A4 | OPTIMIZED MINIZYMES AND MINIRIBOZYMES AND USES THEREOF | COMMW SCIENT IND RES ORG (AU) | 2003-05-21 | — | — | EP | disclosed |
| EP-0693514-B1 | AMIDES AND ETHERS OF PERFLUOROPOLYOXYALKYLENE SULPHONIC- OR PERFLUOROPOLYOXYALKYLENE CARBOXYLIC ACIDS AND A METHOD OF OBTAINING THE SAME | AVTOKONINVEST AO (RU) | 2001-08-01 | — | — | EP | disclosed |
| EP-0837933-A1 | OPTIMIZED MINIZYMES AND MINIRIBOZYMES AND USES THEREOF | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1998-04-29 | — | — | EP | disclosed |
| US-5606098-A | Amides and esters of perfluoropolyoxaalkylene-sulfo- or perfluoropolyoxaalkylene-carboxylic acids and a process for producing same | AO "AVTOKONINVEST" (RU) | 1997-02-25 | — | — | US | disclosed |
| EP-0457550-B1 | Partially crosslinked thermoplastic resin composition | NIPPON PETROCHEMICALS CO LTD (JP) | 1997-01-02 | — | — | EP | disclosed |
| WO-1996040906-A1 | OPTIMIZED MINIZYMES AND MINIRIBOZYMES AND USES THEREOF | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 1996-12-19 | — | — | WO | disclosed |
| EP-0693514-A1 | AMIDES AND ETHERS OF PERFLUOROPOLYOXYALKYLENE SULPHONIC- OR PERFLUOROPOLYOXYALKYLENE CARBOXYLIC ACIDS AND A METHOD OF OBTAINING THE SAME | AO "Avtokoninvest" (RU) | 1996-01-24 | — | — | EP | disclosed |