Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.44 |
| ▸ | FDPS | P14324 | 12/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11322033 | 0.95 | SMPD1 (0.50) | SMPD1FDPSS1PR2S1PR4S1PR1 | |
| SCHEMBL11327549 | 0.94 | SMPD1 (0.53) | SMPD1FDPSS1PR2S1PR4S1PR1 | |
| SCHEMBL11253572 | 0.90 | SMPD1 (0.39) | SMPD1FDPSS1PR2S1PR4S1PR1 | |
| SCHEMBL17923915 | 0.83 | SMPD1 (0.46) | SMPD1FDPSS1PR2S1PR4S1PR1 | |
| SCHEMBL11208828 | 0.83 | SMPD1 (0.33) | SMPD1 | |
| SCHEMBL11310316 | 0.79 | — | — | |
| SCHEMBL11308334 | 0.79 | CYP3A4 (0.38) | SMPD1FDPS | |
| SCHEMBL11327490 | 0.75 | — | — | |
| SCHEMBL11245641 | 0.75 | SMPD1 (0.37) | SMPD1LPAR3LPAR1LPAR2 | |
| SCHEMBL28653187 | 0.73 | SMPD1 (0.57) | SMPD1FDPSGGPS1LPAR3LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257987-A | SYNERGISTIC ARTHROPODICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-03-24 | — | — | US | disclosed |