SCHEMBL11324801

SCHEMBL11324801

CCCCCCCCCCCNc1ccc(Cl)c(Cl)c1

nearest known ligand 0.73

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.73
EPHX2 P34913 1/20 0.48
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
MAPT P10636 1/20 0.45
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CYP3A4 P08684 1/20 0.45
PNLIP P16233 1/20 0.45
GRIN1 Q05586 3/20 0.44
GRIN2B Q13224 3/20 0.44
KCNH2 Q12809 1/20 0.44
AVPR2 P30518 1/20 0.43
DHFR P00374 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KCNH3 Q9ULD8 1/20 0.42
GPR84 Q9NQS5 5/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11332987 1.00 ABL1 (0.73) ABL1EPHX2MEN1KMT2AMAPT
SCHEMBL11332024 1.00 ABL1 (0.73) ABL1EPHX2MEN1KMT2AMAPT
SCHEMBL7647728 1.00 ABL1 (0.73) ABL1EPHX2MEN1KMT2AMAPT
SCHEMBL11332010 1.00 ABL1 (0.73) ABL1EPHX2MEN1KMT2AMAPT
SCHEMBL11338034 1.00 ABL1 (0.73) ABL1EPHX2MEN1KMT2AMAPT
SCHEMBL11331995 1.00 ABL1 (0.73) ABL1EPHX2MEN1KMT2AMAPT
SCHEMBL11327501 0.98 ABL1 (0.71) ABL1EPHX2MEN1KMT2AMAPT
SCHEMBL6950384 0.93 ABL1 (0.63) ABL1EPHX2MEN1KMT2AMAPT
SCHEMBL3393682 0.85 ABL1 (0.53) ABL1EPHX2MEN1KMT2AMAPT
SCHEMBL2446050 0.85 ABL1 (0.68) ABL1EPHX2MEN1KMT2APNLIP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0002721-B1 PROCESS FOR PREPARING HYDRAZINES BAYER AG (DE) 1981-09-02 EP disclosed
EP-0002721-A2 Process for preparing hydrazines BAYER AG (DE) 1979-07-11 EP disclosed