Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17764938 | 0.96 | TSHR (0.41) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11473342 | 0.89 | TSHR (0.45) | TSHRHPGDALDH1A1TP53HIF1A | |
| Hydrochloric Acid SCHEMBL5438217 | 0.87 | TSHR (0.43) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL8603913 | 0.85 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL17764944 | 0.81 | TSHR (0.40) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11348750 | 0.79 | TSHR (0.41) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL15114 | 0.78 | TSHR (0.43) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11456917 | 0.78 | TSHR (0.43) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11695477 | 0.77 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A | |
| Fluoride SCHEMBL1303032 | 0.77 | TSHR (0.42) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4115232-A | ACTINIC RADIATION | ROHM AND HAAS COMPANY (US) | 1978-09-19 | — | — | US | claimed |
| US-4277319-A | N-SUBSTITUTED ACRYOYLOXYETHYLAMINES | ROHM AND HAAS COMPANY (US) | 1981-07-07 | — | — | US | disclosed |
| US-4115232-A | ACTINIC RADIATION | ROHM AND HAAS COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4001304-A | RADIATION CURABLE COATINGS | ROHM AND HAAS COMPANY (US) | 1977-01-04 | — | — | US | disclosed |