Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | PTAFR | P25105 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PDE1A | P54750 | 1/20 | 0.46 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320550 | 0.87 | MEN1 (0.46) | KCNH2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7323663 | 0.84 | KCNH2 (0.48) | KCNH2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7331402 | 0.82 | KCNH2 (0.44) | KCNH2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7458407 | 0.82 | PDE3B (0.64) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL7330234 | 0.81 | MEN1 (0.44) | KCNH2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7332778 | 0.80 | KCNH2 (0.47) | KCNH2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL6649402 | 0.80 | KDM1A (0.47) | KCNH2MEN1KMT2AKDM4EALDH1A1 | |
| Oxalic Acid SCHEMBL7357711 | 0.80 | MEN1 (0.52) | KCNH2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL11312303 | 0.79 | PDE3B (0.71) | KCNH2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL7323611 | 0.79 | KDM1A (0.46) | KCNH2MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4298739-A | ANTICOAGULANTS, ANTIINFLAMMATORY, ANTIULCER, VASODILATOR, PHOSPHODIESTERASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1981-11-03 | — | — | US | disclosed |