Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4131174 | 0.85 | HPGD (0.41) | MEN1KMT2ACYP1A2CYP2C9TP53 | |
| SCHEMBL11322925 | 0.82 | NPSR1 (0.40) | TSHRMEN1KMT2ANPSR1LMNA | |
| SCHEMBL4132447 | 0.80 | PPARG (0.44) | MEN1KMT2AKDM4EHPGDGAA | |
| SCHEMBL777592 | 0.79 | KDM4E (0.42) | TSHRMEN1KMT2ANPSR1KDM4E | |
| SCHEMBL13342841 | 0.78 | TSHR (0.50) | TSHRHTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL3891198 | 0.74 | MAPT (0.53) | MEN1KMT2ACYP1A2CYP2C9LMNA | |
| SCHEMBL4131178 | 0.72 | HPGD (0.40) | MEN1KMT2ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL4135459 | 0.71 | MAPT (0.36) | NPSR1KDM4ECYP1A2LMNAGAA | |
| SCHEMBL18352540 | 0.71 | TSHR (0.50) | TSHRHTR2AHTR2CHTR2BMEN1 | |
| SCHEMBL4131322 | 0.71 | SRC (0.37) | MEN1KMT2AKDM4ETP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4257987-A | SYNERGISTIC ARTHROPODICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1981-03-24 | — | — | US | disclosed |