Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL342450 | 1.00 | SRC (0.46) | SRCPARP1KDM4EALDH1A1MEN1 | |
| SCHEMBL16469336 | 0.96 | SRC (0.44) | SRCPARP1KDM4EALDH1A1MEN1 | |
| SCHEMBL16279870 | 0.96 | SRC (0.44) | SRCPARP1KDM4EALDH1A1MEN1 | |
| Ammonia Solution, Strong SCHEMBL11336651 | 0.96 | SRC (0.44) | SRCPARP1KDM4EALDH1A1MEN1 | |
| SCHEMBL17951854 | 0.96 | SRC (0.50) | SRCPARP1KDM4EALDH1A1MEN1 | |
| SCHEMBL17792659 | 0.96 | SRC (0.50) | SRCPARP1KDM4EALDH1A1MEN1 | |
| Urea SCHEMBL11430458 | 0.85 | SRC (0.43) | SRCPARP1KDM4EALDH1A1LMNA | |
| SCHEMBL11147500 | 0.83 | SRC (0.37) | SRCPARP1KDM4EALDH1A1MEN1 | |
| SCHEMBL11440226 | 0.81 | SRC (0.35) | SRCPARP1 | |
| Acetamide SCHEMBL11256669 | 0.81 | SRC (0.40) | SRCPARP1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4289784-A | ASYMMETRICALLY SUBSTITUTED | MERCK & CO., INC. (US) | 1981-09-15 | — | — | US | disclosed |
| US-4212880-A | INCREASE FEED EFFICIENCY | MERCK & CO., INC. (US) | 1980-07-15 | — | — | US | disclosed |