Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11327052 | 0.98 | ABL1 (0.45) | ABL1GAAALDH1A1HSD17B10CFTR | |
| SCHEMBL8295820 | 0.85 | ABL1 (0.46) | ABL1GAAALDH1A1HSD17B10CFTR | |
| SCHEMBL30279379 | 0.85 | ABL1 (0.46) | ABL1GAAALDH1A1HSD17B10CFTR | |
| SCHEMBL27474595 | 0.84 | ABL1 (0.45) | ABL1GAAALDH1A1HSD17B10CFTR | |
| SCHEMBL3133978 | 0.84 | ABL1 (0.57) | ABL1GAAALDH1A1HSD17B10CFTR | |
| SCHEMBL21435217 | 0.82 | ABL1 (0.47) | ABL1GAAALDH1A1HSD17B10CFTR | |
| SCHEMBL27248606 | 0.82 | GAA (0.49) | ABL1GAAALDH1A1HSD17B10CFTR | |
| SCHEMBL17376170 | 0.82 | ABL1 (0.44) | ABL1GAAALDH1A1HSD17B10CFTR | |
| SCHEMBL30582332 | 0.81 | ABL1 (0.46) | ABL1GAAALDH1A1HSD17B10CFTR | |
| SCHEMBL6137831 | 0.81 | ABL1 (0.46) | ABL1GAAALDH1A1HSD17B10CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002624-B1 | 2-BENZAZEPINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1981-10-14 | — | — | EP | disclosed |
| EP-0002624-A1 | 2-Benzazepine compounds, processes for their preparation and pharmaceutical compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-06-27 | — | — | EP | disclosed |