Ethylene

Ethylene

SCHEMBL11325937

C=C.NCCCOCCCN

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ODC1 P11926 1/20 0.50
NFKB1 P19838 1/20 0.40
CYP3A4 P08684 1/20 0.38
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA2 P00918 2/20 0.38
CA3 P07451 2/20 0.38
CA4 P22748 2/20 0.38
CA6 P23280 2/20 0.38
CA5A P35218 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
CA14 Q9ULX7 2/20 0.38
CA5B Q9Y2D0 2/20 0.38
DNM1 Q05193 1/20 0.38
LMNA P02545 1/20 0.38
TSHR P16473 1/20 0.38
BLM P54132 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL64659 0.93
SCHEMBL6749221 0.89 ODC1 (0.53) ODC1NFKB1CYP3A4CA12CA1
SCHEMBL11126194 0.89 ODC1 (0.53) ODC1NFKB1CYP3A4CA12CA1
Ethylenediamine SCHEMBL10796877 0.89 ODC1 (0.53) ODC1NFKB1CYP3A4CA12CA1
SCHEMBL11556007 0.89 ODC1 (0.53) ODC1NFKB1CYP3A4CA12CA1
SCHEMBL2270584 0.89 ODC1 (0.53) ODC1NFKB1CYP3A4CA12CA1
SCHEMBL2315281 0.89 ODC1 (0.53) ODC1NFKB1CYP3A4CA12CA1
Hydrochloric Acid SCHEMBL6242549 0.89 ODC1 (0.53) ODC1NFKB1CYP3A4CA12CA1
SCHEMBL18756832 0.89 ODC1 (0.53) ODC1NFKB1CYP3A4CA12CA1
SCHEMBL25842 0.89 ODC1 (0.53) ODC1NFKB1CYP3A4CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4267310-A DISPERSION OF A MELTED POLYESTER OR -AMIDE IN AN APROTIC NONSOLVENT CONTAINING A WATER-SOLUBLE BLOCK OR GRAFT POLYMER; COOLING HERCULES INCORPORATED (US) 1981-05-12 US disclosed
US-4002593-A Process for producing dispersions of pigments in condensation type polymers HERCULES INCORPORATED (US) 1977-01-11 US disclosed