Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.74 |
| ▸ | DAO | P14920 | 1/20 | 0.74 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.74 |
| ▸ | CES2 | O00748 | 4/20 | 0.61 |
| ▸ | CES1 | P23141 | 4/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL13733818 | 1.00 | TSHR (0.74) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL2805722 | 0.95 | TSHR (0.82) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28284186 | 0.95 | TSHR (0.82) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL4089578 | 0.95 | TSHR (0.82) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL9456932 | 0.95 | TSHR (0.82) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL29101060 | 0.95 | TSHR (0.82) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL4094227 | 0.95 | TSHR (0.82) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL30542970 | 0.95 | TSHR (0.82) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27772866 | 0.92 | TSHR (0.78) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL31657264 | 0.92 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 639 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109370107-A | A kind of high shock resistance type PVC-U pipe fitting and preparation method thereof | 上海上塑控股（集团）有限公司 | 2019-02-22 | — | — | CN | claimed |
| CN-108440856-A | Dye-colored body and method for producing same | 谦华科技股份有限公司 | 2018-08-24 | — | — | CN | claimed |
| CN-107207817-A | Poly- (vinyl acetal) resin combination, layer and interlayer with enhanced optical characteristics | 首诺公司 | 2017-09-26 | — | — | CN | claimed |
| CN-103562332-B | The hotmelt based on polyolefin containing solid plasticizer | 波士胶公司 | 2017-08-04 | — | — | CN | claimed |
| EP-1171311-B1 | HEAT TRANSFER MATERIAL HAVING A FUSIBLE COATING CONTAINING CYCLOHEXANE DIMETHANOL DIBENZOATE THEREON | NEENAH PAPER INC (US) | 2016-02-03 | — | — | EP | claimed |
| CN-102952490-B | Releasable adhesive sheet | LINTEC CORP. (JP) | 2015-10-28 | — | — | CN | claimed |
| CN-103562332-A | Polyolefin based hot melt adhesive containing a solid plasticizer | BOSTIK INC | 2014-02-05 | — | — | CN | claimed |
| US-20130137789-A1 | POLYVINYL CHLORIDE COMPOSITIONS | EASTMAN CHEMICAL COMPANY (US) | 2013-05-30 | — | — | US | claimed |
| US-8372912-B2 | Polyvinyl chloride compositions | EASTMAN CHEMICAL COMPANY (US) | 2013-02-12 | — | — | US | claimed |
| CN-102449086-A | Activatable adhesives, labels, and related methods | AVERY DENNISON CORP | 2012-05-09 | — | — | CN | claimed |
| JP-2000507283-A | — | — | 2000-06-13 | — | — | JP | claimed |
| US-5945375-A | MULTILAYER; INCLUDES THERMOPLASTIC POLYMER, PLASTICIZER, ANDRELEASE AGENT AT SPECIFIED BASIS WEIGHTS AND WEIGHT RATIOS;NON-IMPACT ELECTRONIC PRINTING GIVING PHOTOGRAPHIC QUALITYPRINTS | KIMBERLY-CLARK WORLDWIDE, INC. (US) | 1999-08-31 | — | — | US | claimed |
| CN-1216552-A | Adhesives comprising olefin polymers | DOW CHEMICAL CO (US) | 1999-05-12 | — | — | CN | claimed |
| EP-0886656-A1 | ADHESIVES COMPRISING OLEFIN POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1998-12-30 | — | — | EP | claimed |
| US-5853864-A | Composite article resistant to moisture-induced debonding | H. B. FULLER LICENSING & FINANCING INC. (US) | 1998-12-29 | — | — | US | claimed |
| WO-1997033921-A1 | ADHESIVES COMPRISING OLEFIN POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1997-09-18 | — | — | WO | claimed |
| US-5627229-A | CYCLOHEXANEDIMETHANOL DIBENZOATE PLASTICIZERS, TACKIFIERS AND TACKIFIER RESINS, COLD FLOW | H.B. FULLER LICENSING & FINANCING, INC. (US) | 1997-05-06 | — | — | US | claimed |
| US-5624986-A | Hot melt adhesive having controlled property change | H. B. FULLER LICENSING & FINANCING INC. (US) | 1997-04-29 | — | — | US | claimed |
| EP-0410412-B1 | Hot melt adhesive having controlled property change | FULLER H B LICENSING FINANC (US) | 1994-01-05 | — | — | EP | claimed |
| EP-0410412-A1 | Hot melt adhesive having controlled property change | H.B. FULLER LICENSING & FINANCING, INC. (US) | 1991-01-30 | — | — | EP | claimed |