Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11329811 | 0.81 | SMN1; SMN2 (0.46) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL11334025 | 0.81 | POLB (0.55) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL27450016 | 0.79 | MAPK1 (0.57) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL11853887 | 0.79 | MAPT (0.50) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL28941770 | 0.79 | CES1 (0.54) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL1532181 | 0.77 | TSHR (0.59) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL21445736 | 0.77 | TDP1 (0.55) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL11760276 | 0.77 | MAPT (0.54) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL11659632 | 0.77 | MEN1 (0.51) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 | |
| SCHEMBL11324917 | 0.77 | KMT2A (0.50) | MAPTMEN1KMT2ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055657-A | S-ARYL-N-ALKYL-THIOLCARBAMATES | PPG INDUSTRIES, INC. (US) | 1977-10-25 | — | — | US | claimed |
| US-4282168-A | FUNGICIDES | PPG INDUSTRIES, INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4055657-A | S-ARYL-N-ALKYL-THIOLCARBAMATES | PPG INDUSTRIES, INC. (US) | 1977-10-25 | — | — | US | disclosed |