SCHEMBL11326545

SCHEMBL11326545

C(=Cc1ccccc1)C=NN=CC=Cc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 2/20 0.67
GRIN3B O60391 2/20 0.67
GRIN1 Q05586 2/20 0.67
GRIN2A Q12879 2/20 0.67
GRIN2B Q13224 2/20 0.67
GRIN2C Q14957 2/20 0.67
GRIN3A Q8TCU5 2/20 0.67
MAOB P27338 1/20 0.65
MAPK1 P28482 3/20 0.54
LMNA P02545 2/20 0.54
TRPA1 O75762 1/20 0.54
ALDH1A1 P00352 1/20 0.54
ALOX5 P09917 1/20 0.54
POLB P06746 2/20 0.50
HTT P42858 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
PLA2G7 Q13093 1/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
NPC1 O15118 5/20 0.47
RAB9A P51151 5/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11778542 1.00 GRIN2D (0.67) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL3153910 0.82 MAOB (0.62) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL21654492 0.82 MAOB (0.62) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL7040853 0.82 MAOB (0.62) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL16472063 0.82 MAOB (0.62) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL17561006 0.81 GRIN2D (1.00) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL17561008 0.81 GRIN2D (1.00) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL13240651 0.80 MAOB (0.59) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL6124740 0.80 MAOB (0.59) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL2651136 0.80 MAOB (0.59) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210231658-A1 Methods and Compositions for Tracking Vegetation COLORADO STATE UNIVERSITY RESEARCH FOUNDATION 2021-07-29 US disclosed
US-4250324-A Water-degradable esters and process for the preparation thereof BEASLEY MARVIN L 1981-02-10 US disclosed
US-3939147-A Novel 1,2-diaza-1,5,9-cyclo dodecatrienes and 1,2-diaza-1-cyclododecenes CIBA-GEIGY CORPORATION (US) 1976-02-17 US disclosed