SCHEMBL1132729

SCHEMBL1132729

CCC(O)C1CCCCC1O

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA4 P22748 2/20 0.43
GBA1 P04062 2/20 0.38
GANAB Q14697 1/20 0.38
SHBG P04278 2/20 0.37
TP53 P04637 1/20 0.34
KDM4E B2RXH2 1/20 0.33
GMNN O75496 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
UGT2B7 P16662 2/20 0.32
SLC6A4 P31645 1/20 0.32
OPRM1 P35372 1/20 0.32
KDR P35968 1/20 0.32
SLC6A3 Q01959 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12676496 0.95 CA1 (0.38) CA1CA2CA4GBA1GANAB
SCHEMBL12676495 0.95 CA1 (0.38) CA1CA2CA4GBA1GANAB
SCHEMBL12676494 0.95 CA1 (0.38) CA1CA2CA4GBA1GANAB
SCHEMBL11730674 0.84 CA1 (0.43) CA1CA2CA4TP53
SCHEMBL6906317 0.82 CA1 (0.42) CA1CA2CA4SHBGTP53
SCHEMBL6909305 0.82 CA1 (0.42) CA1CA2CA4SHBGTP53
SCHEMBL12953219 0.80 CA1 (0.43) CA1CA2CA4GBA1SHBG
SCHEMBL1133177 0.79 CA1 (0.36) CA1CA2CA4TP53KDM4E
SCHEMBL18595189 0.78 CA1 (0.41) CA1CA2CA4GBA1SHBG
SCHEMBL13625288 0.78 TP53 (0.54) CA1CA2CA4TP53KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10364348-B2 Thermoplastic resin composition and molded article comprising the same LOTTE ADVANCED MATERIALS CO., LTD. (KR) 2019-07-30 US disclosed
EP-3135728-B1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING THE SAME LOTTE ADVANCED MAT CO LTD (KR) 2018-03-07 EP disclosed
US-20170058122-A1 Thermoplastic Resin Composition and Molded Article Comprising the Same LOTTE ADVANCED MATERIALS CO., LTD. (KR) 2017-03-02 US disclosed
US-20170058121-A1 Thermoplastic Resin Composition and Molded Article Comprising the Same LOTTE ADVANCED MATERIALS CO., LTD. (KR) 2017-03-02 US disclosed
EP-3135728-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING THE SAME Lotte Advanced Materials Co., Ltd. (KR) 2017-03-01 EP disclosed
EP-2459546-B1 NEW BICYCLIC DIOXANES, THEIR PREPARATION AND THEIR USE AS FRAGRANT COMPOUNDS MANE FILS V (FR) 2013-12-18 EP disclosed
US-8569518-B2 Bicyclic dioxanes, their preparation and their use as fragrant compounds V. MANE FILS (FR) 2013-10-29 US disclosed
US-20120165557-A1 New Bicyclic Dioxanes, Their Preparation and Their Use as Fragrant Compounds V. MANE FILS (FR) 2012-06-28 US disclosed
EP-2459546-A1 NEW BICYCLIC DIOXANES, THEIR PREPARATION AND THEIR USE AS FRAGRANT COMPOUNDS V. Mane Fils (FR) 2012-06-06 EP disclosed
EP-2287159-A1 New bicyclic dioxanes, their preparation and their use as organoleptic compounds V.Mane Fils (FR) 2011-02-23 EP disclosed
WO-2011013077-A1 NEW BICYCLIC DIOXANES, THEIR PREPARATION AND THEIR USE AS FRAGRANT COMPOUNDS V. MANE FILS (FR) 2011-02-03 WO disclosed
EP-1363893-A1 PROCESS FOR PURIFICATION OF WARFARIN ACID, WARFARIN ALKALI METAL SALTS AND CORRESPONDING CLATHRATES TARO PHARMACEUTICALS U.S.A., INC. (US) 2003-11-26 EP disclosed
WO-2002070503-A1 PROCESS FOR PURIFICATION OF WARFARIN ACID, WARFARIN ALKALI METAL SALTS AND CORRESPONDING CLATHRATES TARO PHARMACEUTICALS U.S.A., INC. (US) 2002-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165557-A1 New Bicyclic Dioxanes, Their Preparation and Their Use as Fragrant Compounds CBR3, CCNT1, C1R CA1 3150/4885CA2 4073/4885CA4 3066/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.