Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11342850 | 0.85 | BAZ2B (0.43) | BAZ2BHTR2AHTR2CHTR2BKDR | |
| SCHEMBL11331944 | 0.85 | BAZ2B (0.43) | BAZ2BHTR2AHTR2CHTR2BKDR | |
| SCHEMBL11335646 | 0.85 | HTR2A (0.56) | BAZ2BHTR2AHTR2CHTR2BKDR | |
| SCHEMBL11339601 | 0.85 | BAZ2B (0.43) | BAZ2BHTR2AHTR2CHTR2BKDR | |
| SCHEMBL11330129 | 0.82 | BAZ2B (0.41) | BAZ2BHTR2AHTR2CHTR2BKDR | |
| SCHEMBL11337401 | 0.79 | NOTUM (0.41) | BAZ2BKDRNOTUMMAPT | |
| SCHEMBL11325888 | 0.78 | BAZ2B (0.41) | BAZ2BHTR2AHTR2CHTR2BKDR | |
| SCHEMBL11338653 | 0.78 | BAZ2B (0.41) | BAZ2BHTR2AHTR2CHTR2BKDR | |
| SCHEMBL11325449 | 0.78 | BAZ2B (0.41) | BAZ2BKDRNOTUMMAPTALDH1A1 | |
| SCHEMBL11331930 | 0.78 | BAZ2B (0.43) | BAZ2BKDRNOTUMMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002624-B1 | 2-BENZAZEPINE COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SMITHKLINE BECKMAN CORPORATION (US) | 1981-10-14 | — | — | EP | disclosed |
| EP-0002624-A1 | 2-Benzazepine compounds, processes for their preparation and pharmaceutical compositions containing them | SMITHKLINE BECKMAN CORPORATION (US) | 1979-06-27 | — | — | EP | disclosed |