Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12924873 | 0.84 | KMT2A (0.72) | KMT2ALMNAMEN1MMP8CYP2D6 | |
| SCHEMBL17915488 | 0.83 | KMT2A (0.70) | KMT2ALMNAMEN1MMP8CYP2D6 | |
| SCHEMBL4964029 | 0.83 | KMT2A (0.70) | KMT2AMEN1MMP8CYP2D6CHRM2 | |
| SCHEMBL8021296 | 0.82 | KMT2A (0.46) | KMT2ALMNAMEN1MMP8CYP2D6 | |
| SCHEMBL27900571 | 0.82 | CYP2D6 (0.61) | KMT2ALMNAMEN1CYP2D6CHRM2 | |
| SCHEMBL6752967 | 0.82 | KMT2A (0.81) | KMT2ALMNAMEN1CYP2D6TSHR | |
| SCHEMBL28830824 | 0.82 | KMT2A (0.58) | KMT2ALMNAMEN1MMP8CYP2D6 | |
| SCHEMBL28732213 | 0.80 | KMT2A (0.78) | KMT2ALMNAMEN1MMP8CYP2D6 | |
| SCHEMBL27815900 | 0.80 | KMT2A (0.60) | KMT2ALMNAMEN1CYP2D6TSHR | |
| SCHEMBL27476028 | 0.79 | KMT2A (0.64) | KMT2ALMNAMEN1MMP8CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106512619-B | A kind of equipment and its minimizing technology of high speed rotation inhalation removal industrial dust | 江苏建筑职业技术学院 | 2018-08-21 | — | — | CN | disclosed |
| EP-2632452-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CANCER | ProMetic BioSciences Inc. (CA) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012097427-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CANCER | PROMETIC BIOSCIENCES INC. (CA) | 2012-07-26 | — | — | WO | disclosed |