SCHEMBL1132964

SCHEMBL1132964

C=CC(=O)OC(C)CC[Si](OCCCC)(OCCCC)OCCCC

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.46
HPGD P15428 1/20 0.46
THRB P10828 2/20 0.35
ATM Q13315 1/20 0.34
FAAH O00519 5/20 0.33
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11010730 0.94 TSHR (0.41) TSHRHPGDTHRBFAAHCNR1
SCHEMBL9627890 0.93 TSHR (0.43) TSHRHPGDTHRBATMFAAH
SCHEMBL27979653 0.91 TSHR (0.38) TSHRHPGDALDH1A1CYP3A4
SCHEMBL27989551 0.87 TSHR (0.45) TSHRHPGDTHRBATMFAAH
SCHEMBL27996678 0.86 TSHR (0.44) TSHRHPGDTHRBATMFAAH
SCHEMBL1132650 0.85 TSHR (0.37) TSHRHPGDALDH1A1CYP3A4
SCHEMBL1132460 0.84 TSHR (0.45) TSHRHPGDTHRBATMALDH1A1
SCHEMBL27767311 0.84 TSHR (0.34) TSHRHPGDALDH1A1CYP3A4
SCHEMBL1132453 0.83 TSHR (0.44) TSHRHPGDTHRBATMALDH1A1
SCHEMBL29663927 0.82 TSHR (0.43) TSHRHPGDTHRBATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2287212-B1 A catalyst component for ethylene polymerization, preparation thereof and a catalyst comprising the catalyst component CHINA PETROLEUM & CHEMICAL (CN) 2014-03-26 EP claimed
US-8268945-B2 Catalyst component for ethylene polymerization, preparation thereof, and a catalyst comprising the catalyst component CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-09-18 US claimed
EP-2287212-A1 A catalyst component for ethylene polymerization, preparation thereof and a catalyst comprising the catalyst component China Petroleum & Chemical Corporation (CN) 2011-02-23 EP claimed
CN-113748146-A Polymer dispersions for coating wood for blocking migratable compounds 阿科玛法国公司 2021-12-03 CN disclosed
EP-2287212-B1 A catalyst component for ethylene polymerization, preparation thereof and a catalyst comprising the catalyst component CHINA PETROLEUM & CHEMICAL (CN) 2014-03-26 EP disclosed
US-8268945-B2 Catalyst component for ethylene polymerization, preparation thereof, and a catalyst comprising the catalyst component CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2012-09-18 US disclosed
US-20110046325-A1 CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION, PREPARATION THEREOF, AND A CATALYST COMPRISING THE CATALYST COMPONENT CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2011-02-24 US disclosed
EP-2287212-A1 A catalyst component for ethylene polymerization, preparation thereof and a catalyst comprising the catalyst component China Petroleum & Chemical Corporation (CN) 2011-02-23 EP disclosed