Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11329801 | 0.95 | TDP1 (0.61) | TDP1KMT2AMEN1NR1I2TSHR | |
| SCHEMBL28995 | 0.94 | TDP1 (0.67) | TDP1KMT2AMEN1NR1I2TSHR | |
| Benzene SCHEMBL28227319 | 0.91 | TDP1 (0.63) | TDP1KMT2AMEN1NR1I2TSHR | |
| SCHEMBL9494486 | 0.85 | TDP1 (0.49) | TDP1KMT2AMEN1NR1I2TSHR | |
| SCHEMBL10935492 | 0.83 | TDP1 (0.65) | TDP1KMT2AMEN1NR1I2TSHR | |
| SCHEMBL4372626 | 0.81 | TDP1 (0.51) | TDP1KMT2AMEN1NR1I2TSHR | |
| SCHEMBL29892533 | 0.81 | TDP1 (0.51) | TDP1KMT2AMEN1NR1I2TSHR | |
| SCHEMBL17355868 | 0.79 | TDP1 (0.49) | TDP1KMT2AMEN1NR1I2TSHR | |
| SCHEMBL3228871 | 0.79 | GAA (0.56) | TDP1KMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL3230831 | 0.79 | GAA (0.56) | TDP1KMT2AMEN1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4303766-A | SULFONATION OF ELASTOMERS, FRIEDEL-CRAFTS OR COORDINATION CATALYST, ACYL SULFATE, QUENCHING, NEUTRALIZATION | EXXON RESEARCH & ENGINEERING CO. (US) | 1981-12-01 | — | — | US | disclosed |
| US-4105647-A | SOLUTION POLYMERIZATION USING A FRIEDEL-CRAFTS OF ZIEGLER-TYPE CATALYST | EXXON RESEARCH & ENGINEERING CO. (US) | 1978-08-08 | — | — | US | disclosed |