Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 6/20 | 0.46 |
| ▸ | MMP1 | P03956 | 5/20 | 0.46 |
| ▸ | MMP2 | P08253 | 5/20 | 0.46 |
| ▸ | MMP9 | P14780 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iferanserin SCHEMBL658305 | 0.89 | DRD1 (0.62) | DRD1HRH2HTR2AHTR2COPRK1 | |
| Iferanserin SCHEMBL658304 | 0.89 | DRD1 (0.62) | DRD1HRH2HTR2AHTR2COPRK1 | |
| Iferanserin SCHEMBL4121794 | 0.89 | DRD1 (0.62) | DRD1HRH2HTR2AHTR2COPRK1 | |
| Iferanserin SCHEMBL658953 | 0.88 | DRD1 (0.61) | DRD1HRH2HTR2AHTR2COPRK1 | |
| Iferanserin SCHEMBL659141 | 0.88 | DRD1 (0.61) | DRD1HRH2HTR2AHTR2COPRK1 | |
| SCHEMBL11321421 | 0.83 | HTR2A (0.55) | DRD1HRH2HTR2AHTR2COPRK1 | |
| SCHEMBL10001072 | 0.82 | DRD1 (0.59) | DRD1HRH2HTR2AHTR2COPRK1 | |
| SCHEMBL11324399 | 0.81 | EGFR (0.49) | RAB9ANPC1CYSLTR2CYSLTR1CYP1A2 | |
| SCHEMBL11327431 | 0.78 | CYSLTR2 (0.45) | DRD1HRH2HTR2AHTR2COPRK1 | |
| Water SCHEMBL11331401 | 0.78 | CYSLTR2 (0.44) | DRD1HRH2HTR2AHTR2COPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30812-E | ANTIARRHTHMIA AGENTS | MEAD JOHNSON & COMPANY (US) | 1981-12-01 | — | — | US | disclosed |
| US-RE30811-E | SEROTONIN ANTAGONISTS, ANTIARRHYTHMIA AGENTS | MEAD JOHNSON & COMPANY (US) | 1981-12-01 | — | — | US | disclosed |
| US-4064254-A | ANTIARRHYTHMIC AND ANTISEROTONINE AGENTS | MEAD JOHNSON & COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
| US-4000143-A | ANTIARRHYTHMIC AND ANTISEROTONIN AGENTS | MEAD JOHNSON & COMPANY (US) | 1976-12-28 | — | — | US | disclosed |
| US-3931195-A | ANTIARRHYTHMIA, ANTISEROTONIN | MEAD JOHNSON & COMPANY (US) | 1976-01-06 | — | — | US | disclosed |