Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11329911 | 1.00 | PLK1 (0.47) | PLK1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL11325498 | 1.00 | PLK1 (0.47) | PLK1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL11338770 | 1.00 | PLK1 (0.47) | PLK1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL11329867 | 1.00 | PLK1 (0.47) | PLK1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL11337228 | 1.00 | PLK1 (0.47) | PLK1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL11335028 | 1.00 | PLK1 (0.47) | PLK1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL11331958 | 0.98 | SMN1; SMN2 (0.45) | PLK1HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL183364 | 0.93 | UTS2R (0.48) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL10453656 | 0.87 | SMN1; SMN2 (0.50) | HTR1AADRA1DADRA1AADRA1BSMN1; SMN2 | |
| SCHEMBL5284421 | 0.86 | GUCY1A1 (0.54) | PLK1HTR1AADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002721-B1 | PROCESS FOR PREPARING HYDRAZINES | BAYER AG (DE) | 1981-09-02 | — | — | EP | disclosed |
| EP-0002721-A2 | Process for preparing hydrazines | BAYER AG (DE) | 1979-07-11 | — | — | EP | disclosed |