Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.71 |
| ▸ | PGR | P06401 | 4/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.57 |
| ▸ | SPOP | O43791 | 1/20 | 0.51 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.46 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11332015 | 1.00 | NR1I2 (0.71) | NR1I2TDP1PGRHSD17B10ALDH1A1 | |
| SCHEMBL8869041 | 0.88 | NR1I2 (0.64) | NR1I2TDP1PGRHSD17B10ALDH1A1 | |
| SCHEMBL8869037 | 0.88 | NR1I2 (0.64) | NR1I2TDP1PGRHSD17B10ALDH1A1 | |
| SCHEMBL29709125 | 0.86 | NR1I2 (0.81) | NR1I2TDP1PGRHSD17B10ALDH1A1 | |
| SCHEMBL4610959 | 0.86 | NR1I2 (0.81) | NR1I2TDP1PGRHSD17B10ALDH1A1 | |
| SCHEMBL10555816 | 0.86 | NR1I2 (0.81) | NR1I2TDP1PGRHSD17B10ALDH1A1 | |
| SCHEMBL4750949 | 0.86 | NR1I2 (0.81) | NR1I2TDP1PGRHSD17B10ALDH1A1 | |
| SCHEMBL28375350 | 0.86 | NR1I2 (0.81) | NR1I2TDP1PGRHSD17B10ALDH1A1 | |
| SCHEMBL4610962 | 0.86 | NR1I2 (0.81) | NR1I2TDP1PGRHSD17B10ALDH1A1 | |
| SCHEMBL10643585 | 0.86 | TDP1 (0.56) | NR1I2TDP1PGRHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4256739-A | 7β-Amino-3-thio-3-cephem-4-carboxylic acid compounds, and antibacterial compositions and methods using them | CIBA-GEIGY CORPORATION (US) | 1981-03-17 | — | — | US | disclosed |