Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.60 |
| ▸ | TERT | O14746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LDHA | P00338 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11342337 | 0.80 | IDO1 (0.55) | IDO1TERTMAPTKMT2AMEN1 | |
| SCHEMBL28469527 | 0.78 | CA12 (0.57) | IDO1TERTMAPTKMT2AMEN1 | |
| SCHEMBL8536411 | 0.76 | IDO1 (0.54) | IDO1TERTMAPTKMT2AMEN1 | |
| SCHEMBL10397164 | 0.76 | CA12 (0.65) | KMT2AALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL11660474 | 0.75 | IDO1 (0.54) | IDO1MAPTKMT2AALDH1A1HPGD | |
| SCHEMBL11326356 | 0.75 | HPGD (0.57) | IDO1ALDH1A1SMN1; SMN2HPGDPOLB | |
| SCHEMBL11763230 | 0.74 | PLK1 (0.51) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10824330 | 0.73 | IDO1 (0.47) | IDO1TERTMAPTKMT2AMEN1 | |
| SCHEMBL11660980 | 0.73 | HPGD (0.54) | IDO1MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL7628635 | 0.73 | IDO1 (0.46) | IDO1TERTMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4282168-A | FUNGICIDES | PPG INDUSTRIES, INC. (US) | 1981-08-04 | — | — | US | claimed |
| US-4282168-A | FUNGICIDES | PPG INDUSTRIES, INC. (US) | 1981-08-04 | — | — | US | disclosed |
| US-4055657-A | S-ARYL-N-ALKYL-THIOLCARBAMATES | PPG INDUSTRIES, INC. (US) | 1977-10-25 | — | — | US | disclosed |