Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 7/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2323022 | 0.96 | HRH1 (0.48) | CYP2A6CYP2C9CYP2B6CYP2C19CYP2D6 | |
| SCHEMBL455756 | 0.86 | MAPK1 (0.42) | CYP2A6CYP2C9CYP2B6CYP2C19CYP2D6 | |
| SCHEMBL16458131 | 0.83 | MAPK1 (0.40) | CYP2A6CYP2C9CYP2B6CYP2C19CYP2D6 | |
| SCHEMBL11097956 | 0.83 | SSTR1 (0.43) | LOXL2ALDH1A1 | |
| SCHEMBL5025500 | 0.82 | MAPK1 (0.43) | CYP2A6CYP2C9CYP2B6CYP2C19CYP2D6 | |
| SCHEMBL7686070 | 0.82 | MAPK1 (0.43) | CYP2A6CYP2C9CYP2B6CYP2C19CYP2D6 | |
| SCHEMBL6570950 | 0.82 | MAPK1 (0.39) | CYP2A6CYP2C9CYP2B6CYP2C19CYP2D6 | |
| SCHEMBL1928646 | 0.81 | AKT2 (0.42) | LOXL2ALDH1A1 | |
| SCHEMBL7683895 | 0.80 | MAPK1 (0.42) | CYP2A6CYP2C9CYP2B6CYP2C19CYP2D6 | |
| SCHEMBL19323015 | 0.79 | CYP2A6 (0.46) | CYP2A6CYP2C9CYP2B6CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2287173-A1 | 10A-AZALIDE COMPOUND HAVING 4-MEMBERED RING STRUCTURE | Taisho Pharmaceutical Co., Ltd. (JP) | 2011-02-23 | — | — | EP | disclosed |