Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.52 |
| ▸ | CNR1 | P21554 | 5/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | TRPV2 | Q9Y5S1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11631459 | 0.90 | CNR2 (0.50) | CNR2CNR1TRPA1CYP1A1CYP1A2 | |
| SCHEMBL11332055 | 0.88 | CNR2 (0.66) | CNR2CNR1TRPA1CYP1A1CYP1A2 | |
| SCHEMBL11328743 | 0.88 | CNR2 (0.66) | CNR2CNR1TRPA1CYP1A1CYP1A2 | |
| SCHEMBL11332428 | 0.88 | CNR2 (0.66) | CNR2CNR1TRPA1CYP1A1CYP1A2 | |
| SCHEMBL11329053 | 0.88 | CNR2 (0.66) | CNR2CNR1TRPA1CYP1A1CYP1A2 | |
| SCHEMBL11774583 | 0.87 | CNR2 (0.56) | CNR2CNR1TRPA1CYP1A1CYP1A2 | |
| SCHEMBL11336905 | 0.86 | CNR2 (0.67) | CNR2CNR1TRPA1CYP1A1CYP1A2 | |
| SCHEMBL11336617 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL11704170 | 0.85 | — | — | |
| SCHEMBL11328812 | 0.82 | CNR2 (0.56) | CNR2CNR1TRPA1CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4254116-A | ANALGESICS, ANTIDEPRESSANTS, NEUTRALIZING AGENTS | ABBOTT LABORATORIES (US) | 1981-03-03 | — | — | US | disclosed |
| US-4172943-A | ANALGESICS, TRANQUILIZERS, SEDATIVES, ANTIGLAUCOMA AGENTS | ABBOTT LABORATORIES (US) | 1979-10-30 | — | — | US | disclosed |
| US-4152327-A | ANALGESICS, TRANQUILIZERS, SEDATIVES | ABBOTT LABORATORIES (US) | 1979-05-01 | — | — | US | disclosed |
| US-4137232-A | TRANQUILIZERS, ANALGESICS, SEDATIVES, HYPNOTICS | ABBOTT LABORATORIES (US) | 1979-01-30 | — | — | US | disclosed |