SCHEMBL11337495

SCHEMBL11337495

O=P(O)(O)CCN1CCOCCOCCN(CCP(=O)(O)O)CCOCCOCC1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.52
ALDH1A1 P00352 2/20 0.52
ANPEP P15144 1/20 0.52
GLA P06280 1/20 0.47
HSD17B10 Q99714 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.42
KEAP1 Q14145 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CA9 Q16790 1/20 0.42
MMP1 P03956 1/20 0.41
MMP3 P08254 1/20 0.41
MMP8 P22894 1/20 0.41
TDP1 Q9NUW8 1/20 0.40
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
HPGD P15428 1/20 0.39
DUSP3 P51452 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3969202 0.82 TYMS (0.43) ALDH1A1HSD17B10CA12CA1CA2
SCHEMBL3975041 0.82 TYMS (0.43) ALDH1A1HSD17B10CA12CA1CA2
SCHEMBL11340624 0.78 ANPEP (0.55) KDM4EALDH1A1ANPEPGLAHSD17B10
SCHEMBL10308496 0.77 GLA (0.44) KDM4EALDH1A1ANPEPGLAHSD17B10
SCHEMBL10913328 0.76 KDM4E (0.70) KDM4EALDH1A1GLAHSD17B10SMN1; SMN2
SCHEMBL3971700 0.76 ENPP1 (0.38) ALDH1A1HSD17B10CA12CA1CA2
SCHEMBL8109442 0.76 ANPEP (0.57) KDM4EALDH1A1ANPEPGLAHSD17B10
SCHEMBL24625962 0.74 MAPT (0.41) ALDH1A1HSD17B10CA12CA1CA2
Hydrochloric Acid SCHEMBL25311139 0.74 MAPT (0.52) ALDH1A1ANPEPSMN1; SMN2CA12CA1
SCHEMBL235080 0.74 KDM4E (0.65) KDM4EALDH1A1GLAHSD17B10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4288333-A CROWN ETHERS SHELL OIL COMPANY (US) 1981-09-08 US disclosed