Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18010261 | 0.88 | GAA (0.49) | GAAKMT2AMEN1ATMNPSR1 | |
| SCHEMBL4764331 | 0.78 | GAA (0.54) | GAAKMT2AMEN1ATMNPSR1 | |
| SCHEMBL11323599 | 0.77 | GAA (0.50) | GAAKMT2AMEN1ATMNPSR1 | |
| SCHEMBL26490202 | 0.77 | APP (0.52) | GAAKMT2AAPPMEN1ALDH1A1 | |
| SCHEMBL10966364 | 0.76 | GAA (0.51) | GAAKMT2AMEN1ATMNPSR1 | |
| SCHEMBL40193 | 0.76 | GAA (0.51) | GAAKMT2AMEN1ATMNPSR1 | |
| SCHEMBL9487932 | 0.76 | APP (0.52) | GAAKMT2AAPPATMNPSR1 | |
| SCHEMBL10786630 | 0.75 | GAA (0.56) | GAAKMT2AMEN1ATMNPSR1 | |
| SCHEMBL1083078 | 0.75 | GAA (0.56) | GAAKMT2AMEN1ATMNPSR1 | |
| SCHEMBL4443529 | 0.75 | GAA (0.50) | GAAKMT2AMEN1ATMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4293472-A | O-ALKYLHYDROXYBENZYLPROPANE-1,3-DIOL ESTERS CONTAINING SULFIDE GROUPS | ADEKA ARGUS CHEMICAL CO., LTD. | 1981-10-06 | — | — | US | disclosed |