Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11345947 | 0.95 | HCRTR1 (0.46) | HCRTR1SIRT1ALDH1A1HPGDPPARG | |
| SCHEMBL11339147 | 0.87 | HTT (0.48) | ALDH2KDM4E | |
| SCHEMBL11346947 | 0.85 | ALDH2 (0.43) | HCRTR1ALDH1A1HPGDARALDH2 | |
| SCHEMBL11363873 | 0.85 | TDP1 (0.44) | ALDH1A1HPGDALDH2L3MBTL1KDM4E | |
| SCHEMBL11340905 | 0.82 | HCRTR1 (0.46) | HCRTR1SIRT1ALDH1A1HPGDPPARG | |
| SCHEMBL11338343 | 0.81 | PPARG (0.47) | ALDH1A1PPARGPPARAL3MBTL1KCNA3 | |
| SCHEMBL11342495 | 0.81 | MCL1 (0.49) | HCRTR1ALDH1A1HPGDAHRKDM4E | |
| SCHEMBL11351127 | 0.80 | HTT (0.46) | ALDH2KDM4E | |
| SCHEMBL11336242 | 0.80 | ALDH2 (0.42) | HCRTR1ALDH1A1HPGDARALDH2 | |
| SCHEMBL11340659 | 0.79 | HCRTR1 (0.43) | HCRTR1SIRT1ALDH1A1HPGDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0035744-A1 | Dibenzo-furane-oxyalkane carboxylic acid esters, process for their preparation, herbicides containing them and their use as herbicides | BASF Aktiengesellschaft (DE) | 1981-09-16 | — | — | EP | claimed |